SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 2m6r FLAVODOXIN
(Escherichia
coli) 		4 / 7 THR A  59
GLY A  93
ASP A  94
TYR A  97
 None
 0.64A 1bu5A-2m6rA:
17.0		 1bu5A-2m6rA:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 2m6r FLAVODOXIN
(Escherichia
coli) 		4 / 5 HIS A 143
GLU A 142
ALA A  22
HIS A  31
 None
 1.16A 1errA-2m6rA:
undetectable
1errB-2m6rA:
undetectable		 1errA-2m6rA:
22.18
1errB-2m6rA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 2m6r FLAVODOXIN
(Escherichia
coli) 		5 / 12 PHE A  72
THR A  56
PHE A   7
GLY A  88
LEU A  85
 None
 1.44A 3aodC-2m6rA:
undetectable		 3aodC-2m6rA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 2m6r FLAVODOXIN
(Escherichia
coli) 		3 / 3 SER A  78
GLY A  74
SER A  42
 None
 0.69A 3loqA-2m6rA:
3.1		 3loqA-2m6rA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 2m6r FLAVODOXIN
(Escherichia
coli) 		4 / 8 ASP A  49
PRO A  46
TYR A  47
GLN A  82
 None
 0.96A 3oyaA-2m6rA:
undetectable		 3oyaA-2m6rA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2m6r FLAVODOXIN
(Escherichia
coli) 		3 / 3 GLN A 106
THR A  59
ASN A 102
 None
 0.57A 3v4tE-2m6rA:
undetectable		 3v4tE-2m6rA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 2m6r FLAVODOXIN
(Escherichia
coli) 		5 / 12 TYR A  47
VAL A  52
GLN A  82
LEU A  79
LEU A  41
 None
 1.50A 4qztA-2m6rA:
undetectable		 4qztA-2m6rA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 2m6r FLAVODOXIN
(Escherichia
coli) 		4 / 8 GLN A 114
LEU A  45
TRP A  44
LEU A  41
 None
 1.11A 5hs6A-2m6rA:
2.1		 5hs6A-2m6rA:
19.49