SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m72'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QO6_A_CHDA130_0 (LIVER-BASIC FATTY ACID BINDING PROTEIN)	2m72	UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN (Porphyromonas gingivalis)	5 / 12	TYR A 93 LEU A 50 LEU A 47 ALA A 70 VAL A 95	None	1.34A	2qo6A-2m72A: undetectable	2qo6A-2m72A: 23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJX_H_HCZH800_1 (GLUTAMATE RECEPTOR 2)	2m72	UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN (Porphyromonas gingivalis)	4 / 5	LYS A 83 PRO A 84 LEU A 97 SER A 72	None	1.43A	3ijxH-2m72A: undetectable	3ijxH-2m72A: 19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2X_G_TMQG202_1 (DIHYDROFOLATE REDUCTASE)	2m72	UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN (Porphyromonas gingivalis)	5 / 12	ALA A 114 LEU A 9 PRO A 10 VAL A 12 ILE A 69	None	1.05A	4m2xG-2m72A: undetectable	4m2xG-2m72A: 21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNE_A_ACRA602_1 (-)	2m72	UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN (Porphyromonas gingivalis)	5 / 12	GLY A 134 GLY A 135 VAL A 115 PRO A 113 GLY A 130	None	1.10A	6gneA-2m72A: 3.2	6gneA-2m72A: 14.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QO6_A_CHDA130_0","LIVER-BASIC FATTY ACID BINDING PROTEIN","2m72","UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN","Porphyromonas gingivalis",5,"TYR A  93;LEU A  50;LEU A  47;ALA A  70;VAL A  95","None","1.34A","2qo6A-2m72A:undetectable","2qo6A-2m72A:23.84"],["3IJX_H_HCZH800_1","GLUTAMATE RECEPTOR 2","2m72","UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN","Porphyromonas gingivalis",4,"LYS A  83;PRO A  84;LEU A  97;SER A  72","None","1.43A","3ijxH-2m72A:undetectable","3ijxH-2m72A:19.62"],["4M2X_G_TMQG202_1","DIHYDROFOLATE REDUCTASE","2m72","UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN","Porphyromonas gingivalis",5,"ALA A 114;LEU A   9;PRO A  10;VAL A  12;ILE A  69","None","1.05A","4m2xG-2m72A:undetectable","4m2xG-2m72A:21.81"],["6GNE_A_ACRA602_1","-","2m72","UNCHARACTERIZED THIOREDOXIN-LIKE PROTEIN","Porphyromonas gingivalis",5,"GLY A 134;GLY A 135;VAL A 115;PRO A 113;GLY A 130","None","1.10A","6gneA-2m72A:3.2","6gneA-2m72A:14.90"]]