SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m7a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 2m7a UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		4 / 8 GLU A  17
TRP A  19
TYR A  58
ILE A  77
 None
 1.09A 1qvtA-2m7aA:
undetectable		 1qvtA-2m7aA:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2m7a UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 ASP A  42
LEU A  30
GLN A  18
 None
 0.74A 3g4lA-2m7aA:
undetectable		 3g4lA-2m7aA:
14.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2m7a UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 MET A  21
GLN A  22
ARG A  32
 None
 0.87A 5ewzB-2m7aA:
undetectable		 5ewzB-2m7aA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 2m7a UNCHARACTERIZED
PROTEIN
(Escherichia
coli) 		3 / 3 MET A  21
GLN A  22
ARG A  32
 None
 0.97A 5m36A-2m7aA:
undetectable		 5m36A-2m7aA:
17.70