SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F78_B_BEZB1004_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	2m7u	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Thermosynechococ cus elongatus)	4 / 7	VAL A 460 SER A 477 ARG A 452 LEU A 455	None	1.00A	2f78B-2m7uA: undetectable	2f78B-2m7uA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F8D_A_BEZA1001_0 (HTH-TYPE TRANSCRIPTIONAL REGULATOR BENM)	2m7u	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Thermosynechococ cus elongatus)	4 / 6	VAL A 460 SER A 477 ARG A 452 LEU A 455	None	1.11A	2f8dA-2m7uA: undetectable	2f8dA-2m7uA: 22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_C_ACTC502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	2m7u	METHYL-ACCEPTING CHEMOTAXIS PROTEIN (Thermosynechococ cus elongatus)	3 / 3	PRO A 493 ASP A 492 GLU A 491	VRB A 600 (-3.6A) VRB A 600 (-2.8A) None	0.83A	3v4tC-2m7uA: undetectable	3v4tC-2m7uA: 18.03