SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m8h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2m8h RNA-BINDING PROTEIN
7
(Homo
sapiens) 		4 / 5 GLN A  58
PHE A  59
LEU A  33
PHE A  37
 None
 1.43A 3ablC-2m8hA:
undetectable
3ablJ-2m8hA:
undetectable		 3ablC-2m8hA:
15.04
3ablJ-2m8hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2m8h RNA-BINDING PROTEIN
7
(Homo
sapiens) 		4 / 6 GLN A  58
PHE A  59
PHE A  20
LEU A  12
 None
 1.09A 5z85P-2m8hA:
undetectable
5z85W-2m8hA:
undetectable		 5z85P-2m8hA:
15.04
5z85W-2m8hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2m8h RNA-BINDING PROTEIN
7
(Homo
sapiens) 		4 / 6 GLN A  58
PHE A  59
PHE A  20
LEU A  12
 None
 1.13A 5z86C-2m8hA:
undetectable
5z86J-2m8hA:
undetectable		 5z86C-2m8hA:
15.04
5z86J-2m8hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2m8h RNA-BINDING PROTEIN
7
(Homo
sapiens) 		4 / 6 GLN A  58
PHE A  59
PHE A  20
LEU A  12
 None
 1.11A 5z86P-2m8hA:
undetectable
5z86W-2m8hA:
undetectable		 5z86P-2m8hA:
15.04
5z86W-2m8hA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 2m8h RNA-BINDING PROTEIN
7
(Homo
sapiens) 		4 / 7 GLY A  41
ALA A  40
VAL A  21
LEU A  19
 None
 0.79A 6dwnB-2m8hA:
undetectable		 6dwnB-2m8hA:
17.27