SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOQ_A_ROFA502_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	2m9a	E3 UBIQUITIN-PROTEIN LIGASE ZFP91 (Homo sapiens)	3 / 3	ASN A 58 TRP A 59 GLN A 53	None	1.08A	1xoqA-2m9aA: undetectable	1xoqA-2m9aA: 18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XYT_G_TC9G1206_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	2m9a	E3 UBIQUITIN-PROTEIN LIGASE ZFP91 (Homo sapiens)	4 / 7	TYR A 18 CYH A 19 CYH A 16 GLU A 17	None ZN A 101 (-2.3A) ZN A 101 (-2.3A) None	1.25A	2xytG-2m9aA: undetectable	2xytG-2m9aA: 17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_A_CUA601_0 (LACCASE-1)	2m9a	E3 UBIQUITIN-PROTEIN LIGASE ZFP91 (Homo sapiens)	4 / 5	HIS A 90 CYH A 74 ILE A 76 HIS A 95	ZN A 103 (-3.2A) ZN A 103 (-2.3A) ZN A 103 ( 4.8A) ZN A 103 (-3.3A)	1.49A	3qpkA-2m9aA: undetectable	3qpkA-2m9aA: 9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3QPK_B_CUB601_0 (LACCASE-1)	2m9a	E3 UBIQUITIN-PROTEIN LIGASE ZFP91 (Homo sapiens)	4 / 4	HIS A 90 CYH A 74 ILE A 76 HIS A 95	ZN A 103 (-3.2A) ZN A 103 (-2.3A) ZN A 103 ( 4.8A) ZN A 103 (-3.3A)	1.47A	3qpkB-2m9aA: undetectable	3qpkB-2m9aA: 9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KLA_A_ACTA1505_0 (MATERNAL PROTEIN PUMILIO)	2m9a	E3 UBIQUITIN-PROTEIN LIGASE ZFP91 (Homo sapiens)	3 / 3	HIS A 64 LYS A 63 PHE A 69	ZN A 102 (-3.3A) None None	0.67A	5klaA-2m9aA: undetectable	5klaA-2m9aA: 14.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XOQ_A_ROFA502_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","2m9a","E3 UBIQUITIN-PROTEIN LIGASE ZFP91","Homo sapiens",3,"ASN A  58;TRP A  59;GLN A  53","None","1.08A","1xoqA-2m9aA:undetectable","1xoqA-2m9aA:18.21"],["2XYT_G_TC9G1206_1","SOLUBLE ACETYLCHOLINE RECEPTOR","2m9a","E3 UBIQUITIN-PROTEIN LIGASE ZFP91","Homo sapiens",4,"TYR A  18;CYH A  19;CYH A  16;GLU A  17","None; ZN A 101 (-2.3A); ZN A 101 (-2.3A);None","1.25A","2xytG-2m9aA:undetectable","2xytG-2m9aA:17.50"],["3QPK_A_CUA601_0","LACCASE-1","2m9a","E3 UBIQUITIN-PROTEIN LIGASE ZFP91","Homo sapiens",4,"HIS A  90;CYH A  74;ILE A  76;HIS A  95"," ZN A 103 (-3.2A); ZN A 103 (-2.3A); ZN A 103 ( 4.8A); ZN A 103 (-3.3A)","1.49A","3qpkA-2m9aA:undetectable","3qpkA-2m9aA:9.94"],["3QPK_B_CUB601_0","LACCASE-1","2m9a","E3 UBIQUITIN-PROTEIN LIGASE ZFP91","Homo sapiens",4,"HIS A  90;CYH A  74;ILE A  76;HIS A  95"," ZN A 103 (-3.2A); ZN A 103 (-2.3A); ZN A 103 ( 4.8A); ZN A 103 (-3.3A)","1.47A","3qpkB-2m9aA:undetectable","3qpkB-2m9aA:9.94"],["5KLA_A_ACTA1505_0","MATERNAL PROTEIN PUMILIO","2m9a","E3 UBIQUITIN-PROTEIN LIGASE ZFP91","Homo sapiens",3,"HIS A  64;LYS A  63;PHE A  69"," ZN A 102 (-3.3A);None;None","0.67A","5klaA-2m9aA:undetectable","5klaA-2m9aA:14.24"]]