SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2m9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1C4D_A_DVAA8_0 (GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	VAL A 20 TRP A 5 TRP A 30	None	1.40A	1c4dA-2m9lA: undetectable 1c4dB-2m9lA: undetectable	1c4dA-2m9lA: 14.29 1c4dB-2m9lA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XDC_A_DVAA8_0 (GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	VAL A 20 TRP A 27 TRP A 5	None	1.25A	2xdcA-2m9lA: undetectable 2xdcB-2m9lA: undetectable	2xdcA-2m9lA: 14.29 2xdcB-2m9lA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XDC_B_DVAB8_0 (GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	TRP A 5 VAL A 20 TRP A 27	None	1.26A	2xdcA-2m9lA: undetectable 2xdcB-2m9lA: undetectable	2xdcA-2m9lA: 14.29 2xdcB-2m9lA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y5M_A_DVAA8_0 (VAL-GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	VAL A 20 TRP A 27 TRP A 5	None	1.24A	2y5mA-2m9lA: undetectable 2y5mB-2m9lA: undetectable	2y5mA-2m9lA: 14.29 2y5mB-2m9lA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y6N_A_DVAA8_0 (VAL-GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	VAL A 20 TRP A 27 TRP A 5	None	1.24A	2y6nA-2m9lA: undetectable 2y6nB-2m9lA: undetectable	2y6nA-2m9lA: 14.29 2y6nB-2m9lA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y6N_B_DVAB8_0 (VAL-GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	TRP A 5 VAL A 20 TRP A 27	None	1.25A	2y6nA-2m9lA: undetectable 2y6nB-2m9lA: undetectable	2y6nA-2m9lA: 14.29 2y6nB-2m9lA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQ8_A_DVAA8_0 (VAL-GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	VAL A 20 TRP A 5 TRP A 27	None	1.41A	3zq8A-2m9lA: undetectable 3zq8B-2m9lA: undetectable	3zq8A-2m9lA: 14.29 3zq8B-2m9lA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQ8_A_DVAA8_0 (VAL-GRAMICIDIN A)	2m9l	BETA-THERAPHOTOXIN-T P1A (Thrixopelma pruriens)	3 / 3	VAL A 20 TRP A 27 TRP A 5	None	1.34A	3zq8A-2m9lA: undetectable 3zq8B-2m9lA: undetectable	3zq8A-2m9lA: 14.29 3zq8B-2m9lA: 14.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1C4D_A_DVAA8_0","GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"VAL A  20;TRP A   5;TRP A  30","None","1.40A","1c4dA-2m9lA:undetectable;1c4dB-2m9lA:undetectable","1c4dA-2m9lA:14.29;1c4dB-2m9lA:14.29"],["2XDC_A_DVAA8_0","GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"VAL A  20;TRP A  27;TRP A   5","None","1.25A","2xdcA-2m9lA:undetectable;2xdcB-2m9lA:undetectable","2xdcA-2m9lA:14.29;2xdcB-2m9lA:14.29"],["2XDC_B_DVAB8_0","GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"TRP A   5;VAL A  20;TRP A  27","None","1.26A","2xdcA-2m9lA:undetectable;2xdcB-2m9lA:undetectable","2xdcA-2m9lA:14.29;2xdcB-2m9lA:14.29"],["2Y5M_A_DVAA8_0","VAL-GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"VAL A  20;TRP A  27;TRP A   5","None","1.24A","2y5mA-2m9lA:undetectable;2y5mB-2m9lA:undetectable","2y5mA-2m9lA:14.29;2y5mB-2m9lA:14.29"],["2Y6N_A_DVAA8_0","VAL-GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"VAL A  20;TRP A  27;TRP A   5","None","1.24A","2y6nA-2m9lA:undetectable;2y6nB-2m9lA:undetectable","2y6nA-2m9lA:14.29;2y6nB-2m9lA:14.29"],["2Y6N_B_DVAB8_0","VAL-GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"TRP A   5;VAL A  20;TRP A  27","None","1.25A","2y6nA-2m9lA:undetectable;2y6nB-2m9lA:undetectable","2y6nA-2m9lA:14.29;2y6nB-2m9lA:14.29"],["3ZQ8_A_DVAA8_0","VAL-GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"VAL A  20;TRP A   5;TRP A  27","None","1.41A","3zq8A-2m9lA:undetectable;3zq8B-2m9lA:undetectable","3zq8A-2m9lA:14.29;3zq8B-2m9lA:14.29"],["3ZQ8_A_DVAA8_0","VAL-GRAMICIDIN A","2m9l","BETA-THERAPHOTOXIN-TP1A","Thrixopelma pruriens",3,"VAL A  20;TRP A  27;TRP A   5","None","1.34A","3zq8A-2m9lA:undetectable;3zq8B-2m9lA:undetectable","3zq8A-2m9lA:14.29;3zq8B-2m9lA:14.29"]]