SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ma4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		6 / 11 ASP A  57
VAL A  70
ILE A  43
GLY A  83
ILE A  81
ILE A  24
 None
 1.39A 1sdvB-2ma4A:
undetectable		 1sdvB-2ma4A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		4 / 6 LYS A  65
GLU A  64
ALA A  67
VAL A  70
 None
 1.19A 1sn5A-2ma4A:
undetectable		 1sn5A-2ma4A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		6 / 12 ASP A  57
VAL A  70
ILE A  43
GLY A  83
ILE A  81
ILE A  24
 None
 1.22A 2avvB-2ma4A:
undetectable		 2avvB-2ma4A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 10 GLY A  83
GLY A  75
GLN A  76
THR A  77
ARG A  55
 None
 1.11A 2wd9C-2ma4A:
undetectable		 2wd9C-2ma4A:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_2
(PROTEASE)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 9 VAL A  70
ILE A  43
GLY A  83
ILE A  81
ILE A  24
 None
 1.11A 3ekqB-2ma4A:
undetectable		 3ekqB-2ma4A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		6 / 12 ASP A  57
VAL A  70
ILE A  43
GLY A  83
ILE A  81
ILE A  24
 None
 1.37A 3jw2B-2ma4A:
undetectable		 3jw2B-2ma4A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 12 VAL A  70
ILE A  43
GLY A  83
ILE A  81
ILE A  24
 None
 1.01A 3k4vC-2ma4A:
undetectable		 3k4vC-2ma4A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 9 VAL A  70
VAL A  71
ILE A  43
GLY A  41
ALA A  67
 None
 0.94A 4fwdA-2ma4A:
undetectable		 4fwdA-2ma4A:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		6 / 12 ASP A  57
VAL A  70
ILE A  43
GLY A  83
ILE A  81
ILE A  24
 None
 1.31A 4jecA-2ma4A:
undetectable		 4jecA-2ma4A:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_2
(PROTEASE E35D-SQV)		 2ma4 PUTATIVE PERIPLASMIC
PROTEIN
(Salmonella
enterica) 		5 / 9 VAL A  70
ILE A  43
GLY A  83
ILE A  81
ILE A  24
 None
 1.13A 5kqxB-2ma4A:
undetectable		 5kqxB-2ma4A:
19.81