SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mbb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FCN_B_DVAB35_0
(UBIQUITIN)		 2mbb POLYUBIQUITIN-B
(Homo
sapiens) 		4 / 6 GLN B 231
GLU B 234
ILE B 236
PRO B 237
 None
 0.73A 2fcnA-2mbbB:
14.3
2fcnB-2mbbB:
14.2		 2fcnA-2mbbB:
94.87
2fcnB-2mbbB:
94.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FZB_B_SRYB301_1
(STREPTOMYCIN
3''-ADENYLYLTRANSFER
ASE)		 2mbb IMMUNOGLOBULIN
G-BINDING PROTEIN
G/DNA POLYMERASE
IOTA FUSION PROTEIN
POLYUBIQUITIN-B
(Homo
sapiens;
Streptococcus
sp.
'group
G') 		5 / 12 GLU A  73
GLN A  72
ASP A  81
HIS B 268
ILE B 244
 None
 1.45A 6fzbB-2mbbA:
undetectable		 6fzbB-2mbbA:
19.79