SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mbx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2mbx PARVALBUMIN BETA
(Gadus
morhua) 		5 / 10 ALA A  17
PHE A  67
LEU A  78
ALA A  77
PHE A  30
 None
 1.12A 1g5yC-2mbxA:
undetectable		 1g5yC-2mbxA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_0
(AMINOMETHYLTRANSFERA
SE)		 2mbx PARVALBUMIN BETA
(Gadus
morhua) 		5 / 12 LEU A  87
ILE A  98
PHE A  31
MET A 106
LEU A  78
 None
 1.14A 1wsvA-2mbxA:
undetectable		 1wsvA-2mbxA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_B_THHB4001_0
(AMINOMETHYLTRANSFERA
SE)		 2mbx PARVALBUMIN BETA
(Gadus
morhua) 		5 / 12 LEU A  87
ILE A  98
PHE A  31
MET A 106
LEU A  78
 None
 1.15A 1wsvB-2mbxA:
undetectable		 1wsvB-2mbxA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 2mbx PARVALBUMIN BETA
(Gadus
morhua) 		4 / 7 LEU A  64
PHE A  71
PHE A  86
ILE A  98
 None
 0.94A 2opxA-2mbxA:
undetectable		 2opxA-2mbxA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3004_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2mbx PARVALBUMIN BETA
(Gadus
morhua) 		4 / 5 ILE A  51
PHE A 103
ASP A 101
GLU A 102
 None
None
None
CA  A 202 (-2.2A)
 1.18A 3kp6A-2mbxA:
undetectable
3kp6B-2mbxA:
undetectable		 3kp6A-2mbxA:
23.84
3kp6B-2mbxA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 2mbx PARVALBUMIN BETA
(Gadus
morhua) 		4 / 6 ILE A  12
ILE A  50
PHE A  30
LEU A  36
 None
 0.95A 4m51A-2mbxA:
undetectable		 4m51A-2mbxA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 2mbx PARVALBUMIN BETA
(Gadus
morhua) 		5 / 12 ILE A  98
GLY A  99
ASP A  57
ASP A  52
ILE A  51
 None
None
None
CA  A 201 (-2.8A)
None
 0.95A 6emuA-2mbxA:
undetectable		 6emuA-2mbxA:
20.10