SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mcm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O4D_A_ACTA406_0
(INOSITOL
HEXAKISPHOSPHATE
KINASE)		 2mcm MACROMOMYCIN
(Streptomyces
macromomyceticus) 		4 / 7 ASP A  47
THR A  50
PHE A  72
HIS A  69
 None
MRD  A 115 (-4.3A)
None
None
 1.13A 4o4dA-2mcmA:
undetectable		 4o4dA-2mcmA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 2mcm MACROMOMYCIN
(Streptomyces
macromomyceticus) 		5 / 12 PRO A  27
THR A  26
GLU A 103
SER A 101
GLY A  98
 None
None
None
None
MRD  A 113 ( 4.3A)
 1.28A 4q15B-2mcmA:
undetectable		 4q15B-2mcmA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 2mcm MACROMOMYCIN
(Streptomyces
macromomyceticus) 		5 / 12 PRO A  27
THR A  26
GLU A 103
SER A 101
GLY A  98
 None
None
None
None
MRD  A 113 ( 4.3A)
 1.31A 4ydqB-2mcmA:
undetectable		 4ydqB-2mcmA:
10.55