SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mcp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 2mcp IGA-KAPPA MCPC603
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 11 ILE H  95
GLY H 157
THR H 158
LEU H  20
GLY H  10
 None
 1.17A 1i7qA-2mcpH:
2.6		 1i7qA-2mcpH:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 2mcp IGA-KAPPA MCPC603
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 6 PHE H 154
ASP H 211
LEU H  11
THR H  93
 None
 1.21A 4paeA-2mcpH:
undetectable		 4paeA-2mcpH:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_B_BEZB1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 2mcp IGA-KAPPA MCPC603
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 6 GLY H  10
THR H 119
SER H 212
HIS H 210
 None
 1.09A 5ewuB-2mcpH:
undetectable		 5ewuB-2mcpH:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_A_SUEA1202_1
(NS3 PROTEASE)		 2mcp IGA-KAPPA MCPC603
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 9 ARG H  38
ALA H  90
VAL H 120
SER H 121
ASP H  92
 None
 1.35A 6c2mA-2mcpH:
undetectable		 6c2mA-2mcpH:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 2mcp IGA-KAPPA MCPC603
FAB (HEAVY CHAIN)
(Mus
musculus) 		5 / 9 ARG H  38
ALA H  90
VAL H 120
SER H 121
ASP H  92
 None
 1.38A 6c2mB-2mcpH:
undetectable		 6c2mB-2mcpH:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 2mcp IGA-KAPPA MCPC603
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 5 LEU H  18
THR H 117
PRO H 128
ARG H 126
 None
 1.05A 6ew0F-2mcpH:
undetectable		 6ew0F-2mcpH:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 2mcp IGA-KAPPA MCPC603
FAB (HEAVY CHAIN)
(Mus
musculus) 		4 / 6 LEU H  18
THR H 117
PRO H 128
ARG H 126
 None
 1.05A 6ew0G-2mcpH:
undetectable		 6ew0G-2mcpH:
18.22