SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mdi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifA-2mdiA:
undetectable		 1kifA-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifB-2mdiA:
undetectable		 1kifB-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifC-2mdiA:
undetectable		 1kifC-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifD-2mdiA:
undetectable		 1kifD-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifE-2mdiA:
undetectable		 1kifE-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifF-2mdiA:
undetectable		 1kifF-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifG-2mdiA:
undetectable		 1kifG-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.15A 1kifH-2mdiA:
undetectable		 1kifH-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.21A 1ve9A-2mdiA:
undetectable		 1ve9A-2mdiA:
13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 2mdi HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD2
(Homo
sapiens) 		4 / 5 TYR A  34
TYR A  32
ILE A  31
GLY A   1
 None
 1.09A 2du8G-2mdiA:
undetectable		 2du8G-2mdiA:
9.88