SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mdr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 2mdr DOUBLE-STRANDED
RNA-SPECIFIC
ADENOSINE DEAMINASE
(Homo
sapiens) 		4 / 5 VAL A 764
LEU A 792
VAL A 791
PHE A 769
 None
 1.04A 4lb0B-2mdrA:
undetectable		 4lb0B-2mdrA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 2mdr DOUBLE-STRANDED
RNA-SPECIFIC
ADENOSINE DEAMINASE
(Homo
sapiens) 		3 / 3 TYR A 760
LYS A 781
LYS A 777
 None
 1.12A 5dbyA-2mdrA:
undetectable		 5dbyA-2mdrA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 2mdr DOUBLE-STRANDED
RNA-SPECIFIC
ADENOSINE DEAMINASE
(Homo
sapiens) 		5 / 12 GLY A 717
ASN A 796
GLU A 795
LEU A 792
LEU A 789
 None
 0.75A 5nwvA-2mdrA:
undetectable		 5nwvA-2mdrA:
15.18