SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mem'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 2mem SEX COMB ON
MIDLEG-LIKE PROTEIN
2
(Homo
sapiens) 		4 / 8 LEU A 379
ALA A 403
LEU A 371
GLN A 397
 None
 0.78A 3cldB-2memA:
undetectable		 3cldB-2memA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2mem SEX COMB ON
MIDLEG-LIKE PROTEIN
2
(Homo
sapiens) 		5 / 12 GLY A 368
CYH A 458
GLN A 457
LEU A 462
ILE A 376
 None
 1.36A 6md4A-2memA:
undetectable		 6md4A-2memA:
20.83