SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mev'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
(Cardiovirus
A) 		5 / 12 LEU 2 222
LEU 2 232
ALA 2 220
SER 2 225
PHE 2 121
 None
 1.15A 1dfoA-2mev2:
undetectable		 1dfoA-2mev2:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
(Cardiovirus
A) 		5 / 12 LEU 2 222
LEU 2 232
ALA 2 220
SER 2 225
PHE 2 121
 None
 1.14A 1dfoB-2mev2:
undetectable		 1dfoB-2mev2:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
(Cardiovirus
A) 		5 / 12 LEU 2 222
LEU 2 232
ALA 2 220
SER 2 225
PHE 2 121
 None
 1.15A 1dfoC-2mev2:
undetectable		 1dfoC-2mev2:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
(Cardiovirus
A) 		5 / 12 LEU 2 222
LEU 2 232
ALA 2 220
SER 2 225
PHE 2 121
 None
 1.15A 1dfoD-2mev2:
undetectable		 1dfoD-2mev2:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 8 LEU 3 195
GLY 3 116
ALA 3 205
LYS 3 206
 None
 0.86A 2xfsA-2mev3:
undetectable		 2xfsA-2mev3:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1436_1
(ORF12)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 8 LEU 3 195
GLY 3 116
ALA 3 205
LYS 3 206
 None
 0.91A 2xh9A-2mev3:
undetectable		 2xh9A-2mev3:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A;
Cardiovirus
A) 		5 / 12 ARG 2 101
LEU 2 248
GLY 3 132
PRO 3 130
LEU 2 100
 None
 1.20A 2zzmA-2mev2:
undetectable		 2zzmA-2mev2:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		5 / 12 VAL 3  58
ASN 3  56
ILE 3  65
ALA 3  78
THR 3 188
 None
 1.10A 3ddyA-2mev3:
undetectable		 3ddyA-2mev3:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 5 ILE 3 165
TYR 3 104
GLY 3 185
PRO 3 131
 None
 1.03A 3uboB-2mev3:
undetectable		 3uboB-2mev3:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		5 / 12 ASP 3 184
SER 3 166
THR 3 161
ALA 2  49
TYR 3 104
 None
 1.42A 4u15A-2mev3:
undetectable		 4u15A-2mev3:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ACL_A_SASA1111_1
(MCG)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 7 TYR 3  64
GLU 3  66
PRO 3  63
PHE 3 114
 None
 1.13A 5aclA-2mev3:
undetectable		 5aclA-2mev3:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		5 / 12 ASP 3 184
SER 3 166
THR 3 161
ALA 2  49
TYR 3 104
 None
 1.35A 5dsgA-2mev3:
undetectable		 5dsgA-2mev3:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
(Cardiovirus
A) 		4 / 6 THR 2  64
ALA 2 236
THR 2 235
VAL 2  67
 None
 1.01A 5ecoA-2mev2:
undetectable		 5ecoA-2mev2:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP2)
(Cardiovirus
A) 		3 / 3 VAL 2  34
HIS 2  40
VAL 2 241
 None
 0.68A 5jmnC-2mev2:
undetectable		 5jmnC-2mev2:
13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 6 PHE 3 160
THR 3 161
TYR 3 110
TYR 3 104
 None
 1.31A 5lrbA-2mev3:
undetectable		 5lrbA-2mev3:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 8 GLY 3 122
GLN 3 191
LEU 3 195
THR 3 193
 None
 0.90A 5syjB-2mev3:
undetectable		 5syjB-2mev3:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 7 THR 3 111
VAL 3 109
PRO 3  51
ILE 3  50
 None
 0.89A 5vkqA-2mev3:
undetectable
5vkqB-2mev3:
undetectable		 5vkqA-2mev3:
8.61
5vkqB-2mev3:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 8 THR 3 111
VAL 3 109
PRO 3  51
ILE 3  50
 None
 0.89A 5vkqB-2mev3:
undetectable
5vkqC-2mev3:
undetectable		 5vkqB-2mev3:
8.61
5vkqC-2mev3:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 2mev MENGO VIRUS COAT
PROTEIN (SUBUNIT
VP3)
(Cardiovirus
A) 		4 / 7 THR 3 111
VAL 3 109
PRO 3  51
ILE 3  50
 None
 0.91A 5vkqC-2mev3:
undetectable
5vkqD-2mev3:
undetectable		 5vkqC-2mev3:
8.61
5vkqD-2mev3:
8.61