SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mf8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 2mf8 MYELIN TRANSCRIPTION
FACTOR 1
(Mus
musculus) 		4 / 8 THR A 804
PRO A 805
GLY A 806
CYH A 807
 ZN  A 901 (-4.0A)
None
None
ZN  A 901 (-1.9A)
 0.86A 1h4oB-2mf8A:
undetectable		 1h4oB-2mf8A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 2mf8 MYELIN TRANSCRIPTION
FACTOR 1
(Mus
musculus) 		4 / 8 THR A 848
PRO A 849
GLY A 850
CYH A 851
 ZN  A 902 (-3.2A)
None
None
ZN  A 902 (-2.3A)
 0.88A 1h4oB-2mf8A:
undetectable		 1h4oB-2mf8A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 2mf8 MYELIN TRANSCRIPTION
FACTOR 1
(Mus
musculus) 		4 / 8 THR A 804
PRO A 805
GLY A 806
CYH A 807
 ZN  A 901 (-4.0A)
None
None
ZN  A 901 (-1.9A)
 0.82A 1h4oG-2mf8A:
undetectable		 1h4oG-2mf8A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 2mf8 MYELIN TRANSCRIPTION
FACTOR 1
(Mus
musculus) 		4 / 8 THR A 848
PRO A 849
GLY A 850
CYH A 851
 ZN  A 902 (-3.2A)
None
None
ZN  A 902 (-2.3A)
 0.83A 1h4oG-2mf8A:
undetectable		 1h4oG-2mf8A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 2mf8 MYELIN TRANSCRIPTION
FACTOR 1
(Mus
musculus) 		4 / 8 THR A 804
PRO A 805
GLY A 806
CYH A 807
 ZN  A 901 (-4.0A)
None
None
ZN  A 901 (-1.9A)
 0.87A 1oc3A-2mf8A:
undetectable		 1oc3A-2mf8A:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 2mf8 MYELIN TRANSCRIPTION
FACTOR 1
(Mus
musculus) 		4 / 8 THR A 848
PRO A 849
GLY A 850
CYH A 851
 ZN  A 902 (-3.2A)
None
None
ZN  A 902 (-2.3A)
 0.89A 1oc3A-2mf8A:
undetectable		 1oc3A-2mf8A:
22.73