SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mf9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWI_A_CAMA418_0
(CYTOCHROME P450-CAM)		 2mf9 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP8
(Homo
sapiens) 		4 / 8 LEU A 144
VAL A 142
VAL A  95
ASP A 100
 None
 0.95A 1iwiA-2mf9A:
undetectable		 1iwiA-2mf9A:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 2mf9 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP8
(Homo
sapiens) 		5 / 12 ALA A 137
PRO A 134
GLY A 123
LYS A 119
ASP A 117
 None
 1.10A 3m6vA-2mf9A:
undetectable		 3m6vA-2mf9A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 2mf9 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP8
(Homo
sapiens) 		5 / 12 ALA A 137
PRO A 134
GLY A 123
LYS A 119
ASP A 117
 None
 1.09A 3m6vB-2mf9A:
undetectable		 3m6vB-2mf9A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQB_A_FK5A114_1
(UBIQUITIN-LIKE
PROTEIN SMT3,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 2mf9 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP8
(Homo
sapiens) 		4 / 8 VAL A  95
ILE A  96
TYR A 122
ILE A 132
 None
 0.91A 3uqbA-2mf9A:
13.4		 3uqbA-2mf9A:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2mf9 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP8
(Homo
sapiens) 		3 / 3 THR A 146
VAL A 148
GLU A  85
 None
 0.76A 3v4tA-2mf9A:
undetectable
3v4tD-2mf9A:
undetectable		 3v4tA-2mf9A:
17.42
3v4tD-2mf9A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 2mf9 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP8
(Homo
sapiens) 		5 / 11 ILE A  96
THR A  72
VAL A 142
VAL A 103
LEU A  86
 None
 1.36A 5jkwA-2mf9A:
undetectable		 5jkwA-2mf9A:
14.12