SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 2mfi 30S RIBOSOMAL
PROTEIN S1
(Escherichia
coli) 		3 / 3 ARG A  86
ARG A  91
TRP A  95
 None
 1.47A 4cpzC-2mfiA:
undetectable		 4cpzC-2mfiA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2mfi 30S RIBOSOMAL
PROTEIN S1
(Escherichia
coli) 		3 / 3 SER A  22
ALA A  71
VAL A  70
 None
 0.45A 4o2bA-2mfiA:
undetectable		 4o2bA-2mfiA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2mfi 30S RIBOSOMAL
PROTEIN S1
(Escherichia
coli) 		3 / 3 SER A  22
ALA A  71
VAL A  70
 None
 0.45A 4o2bC-2mfiA:
undetectable		 4o2bC-2mfiA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2mfi 30S RIBOSOMAL
PROTEIN S1
(Escherichia
coli) 		3 / 3 SER A  22
ALA A  71
VAL A  70
 None
 0.52A 4x1iA-2mfiA:
undetectable		 4x1iA-2mfiA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2mfi 30S RIBOSOMAL
PROTEIN S1
(Escherichia
coli) 		3 / 3 SER A  22
ALA A  71
VAL A  70
 None
 0.37A 4x20C-2mfiA:
undetectable		 4x20C-2mfiA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2mfi 30S RIBOSOMAL
PROTEIN S1
(Escherichia
coli) 		3 / 3 SER A  22
ALA A  71
VAL A  70
 None
 0.51A 5eypA-2mfiA:
undetectable		 5eypA-2mfiA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 2mfi 30S RIBOSOMAL
PROTEIN S1
(Escherichia
coli) 		3 / 3 SER A  22
ALA A  71
VAL A  70
 None
 0.55A 5xiwC-2mfiA:
undetectable		 5xiwC-2mfiA:
22.86