SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mgz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_A_AERA601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2mgz	PROTEIN ASD-1, ISOFORM A (Caenorhabditis elegans)	5 / 12	LEU A 116 PHE A 120 ILE A 107 THR A 162 VAL A 171	None None G C 2 ( 4.8A) None None	0.94A	4nkvA-2mgzA: undetectable	4nkvA-2mgzA: 12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_B_AERB601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2mgz	PROTEIN ASD-1, ISOFORM A (Caenorhabditis elegans)	5 / 12	LEU A 116 PHE A 120 ILE A 107 THR A 162 VAL A 171	None None G C 2 ( 4.8A) None None	0.94A	4nkvB-2mgzA: undetectable	4nkvB-2mgzA: 12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_C_AERC601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2mgz	PROTEIN ASD-1, ISOFORM A (Caenorhabditis elegans)	5 / 12	LEU A 116 PHE A 120 ILE A 107 THR A 162 VAL A 171	None None G C 2 ( 4.8A) None None	0.94A	4nkvC-2mgzA: undetectable	4nkvC-2mgzA: 12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKV_D_AERD601_1 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	2mgz	PROTEIN ASD-1, ISOFORM A (Caenorhabditis elegans)	5 / 12	LEU A 116 PHE A 120 ILE A 107 THR A 162 VAL A 171	None None G C 2 ( 4.8A) None None	0.94A	4nkvD-2mgzA: undetectable	4nkvD-2mgzA: 12.64

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4NKV_A_AERA601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2mgz","PROTEIN ASD-1, ISOFORM A","Caenorhabditis elegans",5,"LEU A 116;PHE A 120;ILE A 107;THR A 162;VAL A 171","None;None;  G C   2 ( 4.8A);None;None","0.94A","4nkvA-2mgzA:undetectable","4nkvA-2mgzA:12.64"],["4NKV_B_AERB601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2mgz","PROTEIN ASD-1, ISOFORM A","Caenorhabditis elegans",5,"LEU A 116;PHE A 120;ILE A 107;THR A 162;VAL A 171","None;None;  G C   2 ( 4.8A);None;None","0.94A","4nkvB-2mgzA:undetectable","4nkvB-2mgzA:12.64"],["4NKV_C_AERC601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2mgz","PROTEIN ASD-1, ISOFORM A","Caenorhabditis elegans",5,"LEU A 116;PHE A 120;ILE A 107;THR A 162;VAL A 171","None;None;  G C   2 ( 4.8A);None;None","0.94A","4nkvC-2mgzA:undetectable","4nkvC-2mgzA:12.64"],["4NKV_D_AERD601_1","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","2mgz","PROTEIN ASD-1, ISOFORM A","Caenorhabditis elegans",5,"LEU A 116;PHE A 120;ILE A 107;THR A 162;VAL A 171","None;None;  G C   2 ( 4.8A);None;None","0.94A","4nkvD-2mgzA:undetectable","4nkvD-2mgzA:12.64"]]