SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mhc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 2mhc TNPX
(Clostridium
perfringens) 		4 / 5 LEU A  79
PHE A  64
VAL A  71
ALA A   9
 None
 1.01A 2cizA-2mhcA:
undetectable		 2cizA-2mhcA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9D_A_ACTA1117_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 2mhc TNPX
(Clostridium
perfringens) 		3 / 3 ASP A  51
ARG A  61
ARG A  13
 None
 0.57A 2j9dA-2mhcA:
undetectable
2j9dC-2mhcA:
undetectable		 2j9dA-2mhcA:
21.05
2j9dC-2mhcA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK7_B_SAMB770_0
(23S RRNA
METHYLTRANSFERASE)		 2mhc TNPX
(Clostridium
perfringens) 		5 / 12 ASN A  90
LEU A 101
PHE A  96
GLY A  95
ILE A  68
 None
 0.93A 3nk7B-2mhcA:
undetectable		 3nk7B-2mhcA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 2mhc TNPX
(Clostridium
perfringens) 		3 / 3 GLN A  93
PHE A  96
TYR A  97
 None
 0.98A 3ucjB-2mhcA:
3.3		 3ucjB-2mhcA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 2mhc TNPX
(Clostridium
perfringens) 		3 / 3 ASP A 117
ASN A 114
PHE A  96
 None
 0.74A 5jglB-2mhcA:
undetectable		 5jglB-2mhcA:
19.51