SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mhf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2mhf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 GLY A  70
GLY A  68
ILE A  73
TYR A  48
THR A  28
 None
 1.02A 1p91B-2mhfA:
undetectable		 1p91B-2mhfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)		 2mhf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 LEU A  98
ALA A  32
ALA A  92
MET A  55
LEU A  67
 None
 1.28A 1rbpA-2mhfA:
undetectable		 1rbpA-2mhfA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 2mhf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 7 LEU A  67
LEU A 132
ILE A  38
MET A  55
 None
 1.03A 2qqdA-2mhfA:
undetectable
2qqdE-2mhfA:
undetectable		 2qqdA-2mhfA:
25.49
2qqdE-2mhfA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2mhf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 11 LEU A  98
ALA A  32
ALA A  92
MET A  55
LEU A  67
 None
 1.29A 3bszE-2mhfA:
undetectable		 3bszE-2mhfA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 2mhf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 5 ASP A  76
LEU A  78
ILE A  73
PHE A  49
 None
 1.08A 3s3vA-2mhfA:
undetectable		 3s3vA-2mhfA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2mhf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		4 / 7 ILE A  84
LEU A  44
THR A  79
LEU A  78
 None
 0.96A 5xdqN-2mhfA:
undetectable
5xdqW-2mhfA:
undetectable		 5xdqN-2mhfA:
14.06
5xdqW-2mhfA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 2mhf UNCHARACTERIZED
PROTEIN
(Danio
rerio) 		5 / 12 VAL A  57
GLY A  74
ILE A  47
LEU A  64
VAL A  90
 None
 0.90A 6dh0B-2mhfA:
undetectable		 6dh0B-2mhfA:
18.98