SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mhl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TKQ_B_DVAB8_0 (GRAMICIDIN A)	2mhl	OUTER MEMBRANE PROTEIN W (Escherichia coli)	4 / 5	VAL A 101 GLY A 102 VAL A 139 TRP A 156	None	1.35A	1tkqB-2mhlA: undetectable	1tkqB-2mhlA: 14.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_W_CHDW1060_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	2mhl	OUTER MEMBRANE PROTEIN W (Escherichia coli)	4 / 5	TYR A 190 MET A 9 THR A 43 LEU A 42	None	1.42A	2eimW-2mhlA: undetectable	2eimW-2mhlA: 13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_A_ANWA99_0 (PROTEIN S100-A13)	2mhl	OUTER MEMBRANE PROTEIN W (Escherichia coli)	4 / 7	MET A 47 PHE A 44 THR A 43 ARG A 10	None	1.08A	2kotA-2mhlA: undetectable	2kotA-2mhlA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG2_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	2mhl	OUTER MEMBRANE PROTEIN W (Escherichia coli)	4 / 5	TYR A 190 MET A 9 THR A 43 LEU A 42	None	1.44A	3ag2J-2mhlA: undetectable	3ag2J-2mhlA: 13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG4_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	2mhl	OUTER MEMBRANE PROTEIN W (Escherichia coli)	4 / 5	TYR A 190 MET A 9 THR A 43 LEU A 42	None	1.44A	3ag4J-2mhlA: undetectable	3ag4J-2mhlA: 13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM6_A_017A200_1 (PROTEASE)	2mhl	OUTER MEMBRANE PROTEIN W (Escherichia coli)	4 / 8	GLY A 189 ALA A 188 GLY A 12 LEU A 42	None	0.60A	3em6A-2mhlA: undetectable	3em6A-2mhlA: 16.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TKQ_B_DVAB8_0","GRAMICIDIN A","2mhl","OUTER MEMBRANE PROTEIN W","Escherichia coli",4,"VAL A 101;GLY A 102;VAL A 139;TRP A 156","None","1.35A","1tkqB-2mhlA:undetectable","1tkqB-2mhlA:14.63"],["2EIM_W_CHDW1060_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","2mhl","OUTER MEMBRANE PROTEIN W","Escherichia coli",4,"TYR A 190;MET A   9;THR A  43;LEU A  42","None","1.42A","2eimW-2mhlA:undetectable","2eimW-2mhlA:13.98"],["2KOT_A_ANWA99_0","PROTEIN S100-A13","2mhl","OUTER MEMBRANE PROTEIN W","Escherichia coli",4,"MET A  47;PHE A  44;THR A  43;ARG A  10","None","1.08A","2kotA-2mhlA:undetectable","2kotA-2mhlA:15.98"],["3AG2_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","2mhl","OUTER MEMBRANE PROTEIN W","Escherichia coli",4,"TYR A 190;MET A   9;THR A  43;LEU A  42","None","1.44A","3ag2J-2mhlA:undetectable","3ag2J-2mhlA:13.98"],["3AG4_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","2mhl","OUTER MEMBRANE PROTEIN W","Escherichia coli",4,"TYR A 190;MET A   9;THR A  43;LEU A  42","None","1.44A","3ag4J-2mhlA:undetectable","3ag4J-2mhlA:13.98"],["3EM6_A_017A200_1","PROTEASE","2mhl","OUTER MEMBRANE PROTEIN W","Escherichia coli",4,"GLY A 189;ALA A 188;GLY A  12;LEU A  42","None","0.60A","3em6A-2mhlA:undetectable","3em6A-2mhlA:16.00"]]