SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mi6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 2mi6 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSG
(Mycobacterium
tuberculosis) 		3 / 3 LEU A  25
PRO A  26
ARG A  48
 None
 0.65A 2qd5A-2mi6A:
undetectable		 2qd5A-2mi6A:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2mi6 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSG
(Mycobacterium
tuberculosis) 		3 / 3 LEU A  25
PRO A  26
ARG A  48
 None
 0.75A 4klrB-2mi6A:
undetectable		 4klrB-2mi6A:
10.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 2mi6 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSG
(Mycobacterium
tuberculosis) 		4 / 6 THR A  16
ALA A  27
LEU A  42
SER A  30
 None
 1.03A 4pwjA-2mi6A:
undetectable		 4pwjA-2mi6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 2mi6 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSG
(Mycobacterium
tuberculosis) 		4 / 7 THR A  16
ALA A  27
LEU A  42
SER A  30
 None
 1.01A 4pwjB-2mi6A:
undetectable		 4pwjB-2mi6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 2mi6 TRANSCRIPTION
TERMINATION/ANTITERM
INATION PROTEIN NUSG
(Mycobacterium
tuberculosis) 		4 / 7 THR A  16
ALA A  27
LEU A  42
SER A  30
 None
 1.05A 5bojB-2mi6A:
undetectable		 5bojB-2mi6A:
22.83