SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2miz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 2miz M04 IMMUNOEVASIN
(Murid
betaherpesvirus
1) 		3 / 3 VAL A  71
VAL A  64
TRP A  62
 None
 0.75A 1av2A-2mizA:
undetectable
1av2B-2mizA:
undetectable		 1av2A-2mizA:
6.94
1av2B-2mizA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 2miz M04 IMMUNOEVASIN
(Murid
betaherpesvirus
1) 		3 / 3 VAL A  71
VAL A  64
TRP A  62
 None
 0.89A 1w5uA-2mizA:
undetectable
1w5uB-2mizA:
undetectable		 1w5uA-2mizA:
6.94
1w5uB-2mizA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC1383_1
(CES1 PROTEIN)		 2miz M04 IMMUNOEVASIN
(Murid
betaherpesvirus
1) 		4 / 5 TRP A  58
PRO A  50
LEU A 172
GLY A  30
 None
 1.38A 1ya4C-2mizA:
undetectable		 1ya4C-2mizA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 2miz M04 IMMUNOEVASIN
(Murid
betaherpesvirus
1) 		3 / 3 VAL A  64
TRP A  62
VAL A  71
 None
 0.78A 2izqC-2mizA:
undetectable
2izqD-2mizA:
undetectable		 2izqC-2mizA:
6.94
2izqD-2mizA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_1
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 2miz M04 IMMUNOEVASIN
(Murid
betaherpesvirus
1) 		3 / 3 SER A  70
ASP A 110
ASP A  72
 None
 0.77A 2plwA-2mizA:
undetectable		 2plwA-2mizA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2miz M04 IMMUNOEVASIN
(Murid
betaherpesvirus
1) 		4 / 7 VAL A  73
ALA A  90
GLY A 124
VAL A 114
 None
 0.88A 5fpdB-2mizA:
undetectable		 5fpdB-2mizA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2miz M04 IMMUNOEVASIN
(Murid
betaherpesvirus
1) 		3 / 3 GLY A  25
VAL A 169
MET A 166
 None
 0.55A 5ycpA-2mizA:
undetectable		 5ycpA-2mizA:
16.75