SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mj3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2mj3 IRON-SULFUR CLUSTER
BINDING PROTEIN
(Ehrlichia
chaffeensis) 		4 / 5 GLU A  61
TYR A  57
PRO A  54
ASP A  58
 None
 1.17A 1i7zB-2mj3A:
0.0		 1i7zB-2mj3A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_C_COCC302_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 2mj3 IRON-SULFUR CLUSTER
BINDING PROTEIN
(Ehrlichia
chaffeensis) 		4 / 4 GLU A  61
TYR A  57
PRO A  54
ASP A  58
 None
 1.16A 1i7zD-2mj3A:
0.0		 1i7zD-2mj3A:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 2mj3 IRON-SULFUR CLUSTER
BINDING PROTEIN
(Ehrlichia
chaffeensis) 		5 / 9 GLY A  11
SER A   8
LEU A 103
ASP A  10
GLU A 106
 None
 1.39A 2j2pB-2mj3A:
undetectable
2j2pC-2mj3A:
undetectable		 2j2pB-2mj3A:
18.35
2j2pC-2mj3A:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2mj3 IRON-SULFUR CLUSTER
BINDING PROTEIN
(Ehrlichia
chaffeensis) 		4 / 4 GLU A  17
PRO A   2
ILE A   4
LEU A   3
 None
 1.23A 5m45A-2mj3A:
undetectable		 5m45A-2mj3A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2mj3 IRON-SULFUR CLUSTER
BINDING PROTEIN
(Ehrlichia
chaffeensis) 		4 / 4 GLU A  17
PRO A   2
ILE A   4
LEU A   3
 None
 1.29A 5m45D-2mj3A:
undetectable		 5m45D-2mj3A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2mj3 IRON-SULFUR CLUSTER
BINDING PROTEIN
(Ehrlichia
chaffeensis) 		4 / 4 GLU A  17
PRO A   2
ILE A   4
LEU A   3
 None
 1.24A 5m45G-2mj3A:
undetectable		 5m45G-2mj3A:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 2mj3 IRON-SULFUR CLUSTER
BINDING PROTEIN
(Ehrlichia
chaffeensis) 		4 / 4 GLU A  17
PRO A   2
ILE A   4
LEU A   3
 None
 1.28A 5m45J-2mj3A:
undetectable		 5m45J-2mj3A:
8.25