SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mje'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 2mje ADRENODOXIN HOMOLOG,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 10 GLU A   2
LEU A   4
MET A  91
ILE A  29
HIS A  33
 None
 1.42A 1qkuA-2mjeA:
undetectable		 1qkuA-2mjeA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 2mje ADRENODOXIN HOMOLOG,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 10 GLU A   2
LEU A   4
MET A  91
ILE A  29
HIS A  33
 None
 1.42A 1qkuB-2mjeA:
undetectable		 1qkuB-2mjeA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 2mje ADRENODOXIN HOMOLOG,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 10 GLU A   2
LEU A   4
MET A  91
ILE A  29
HIS A  33
 None
 1.42A 1qkuC-2mjeA:
undetectable		 1qkuC-2mjeA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 2mje ADRENODOXIN HOMOLOG,
MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 4 ARG A 107
ASP A 113
GLY A  43
THR A  49
 None
 1.44A 3k4vB-2mjeA:
undetectable		 3k4vB-2mjeA:
22.05