SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mjf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA CHAIN)		 2mjf PROTEIN HIT1
(Saccharomyces
cerevisiae) 		4 / 8 LYS B  75
VAL B  76
TYR B 104
LEU B 105
 None
 1.01A 1z2bB-2mjfB:
undetectable		 1z2bB-2mjfB:
13.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2mjf PROTEIN HIT1
RIBOSOME ASSEMBLY 1
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 LEU B  73
TYR B  77
ALA B 101
LEU A  25
 None
 0.65A 3ravA-2mjfB:
undetectable		 3ravA-2mjfB:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 2mjf PROTEIN HIT1
RIBOSOME ASSEMBLY 1
PROTEIN
(Saccharomyces
cerevisiae) 		4 / 6 LEU B  73
TYR B  77
ALA B 101
LEU A  25
 None
 0.65A 3rd0A-2mjfB:
undetectable		 3rd0A-2mjfB:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2mjf RIBOSOME ASSEMBLY 1
PROTEIN
PROTEIN HIT1
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 10 GLY A  20
GLY A  23
LEU A  25
LEU B  64
TYR B  54
 None
 1.11A 5hwkA-2mjfA:
undetectable		 5hwkA-2mjfA:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2mjf RIBOSOME ASSEMBLY 1
PROTEIN
PROTEIN HIT1
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 10 GLY A  20
GLY A  23
LEU A  25
LEU B  64
TYR B  54
 None
 1.11A 5hwkB-2mjfA:
undetectable		 5hwkB-2mjfA:
13.98