SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 2mjl PEPTIDYL-TRNA
HYDROLASE
(Vibrio
cholerae) 		5 / 11 ALA A  77
LEU A  12
ALA A  13
ALA A  28
LEU A  65
 None
 1.01A 1jinA-2mjlA:
undetectable		 1jinA-2mjlA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 2mjl PEPTIDYL-TRNA
HYDROLASE
(Vibrio
cholerae) 		5 / 10 ILE A  87
ALA A  82
PRO A   5
GLU A  91
ILE A   6
 None
 1.04A 2dm6A-2mjlA:
undetectable
2dm6B-2mjlA:
undetectable		 2dm6A-2mjlA:
22.56
2dm6B-2mjlA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)		 2mjl PEPTIDYL-TRNA
HYDROLASE
(Vibrio
cholerae) 		5 / 8 LEU A  65
ALA A  77
GLY A  11
LEU A  12
GLY A 119
 None
 1.41A 2yfxA-2mjlA:
undetectable		 2yfxA-2mjlA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AV6_A_SAMA1_0
(DNA
(CYTOSINE-5)-METHYLT
RANSFERASE 1)		 2mjl PEPTIDYL-TRNA
HYDROLASE
(Vibrio
cholerae) 		5 / 12 GLY A  11
LEU A  51
MET A  93
LEU A  62
ALA A  28
 None
 0.92A 3av6A-2mjlA:
undetectable		 3av6A-2mjlA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 2mjl PEPTIDYL-TRNA
HYDROLASE
(Vibrio
cholerae) 		5 / 12 GLY A  75
LEU A  65
PHE A  49
LEU A  73
ALA A  80
 None
 1.01A 3kkzA-2mjlA:
undetectable		 3kkzA-2mjlA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2mjl PEPTIDYL-TRNA
HYDROLASE
(Vibrio
cholerae) 		3 / 3 ASN A  72
LEU A  12
PHE A  49
 None
 0.73A 4dajB-2mjlA:
undetectable		 4dajB-2mjlA:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2mjl PEPTIDYL-TRNA
HYDROLASE
(Vibrio
cholerae) 		4 / 8 ALA A  28
PRO A  67
LEU A  51
LEU A  65
 None
 1.13A 5dzkd-2mjlA:
undetectable
5dzkr-2mjlA:
undetectable		 5dzkd-2mjlA:
21.37
5dzkr-2mjlA:
22.22