SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mjm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MX1_B_THAB2_1 (LIVER CARBOXYLESTERASE I)	2mjm	PROTEIN NLRC5 (Mus musculus)	5 / 11	LEU A 80 PHE A 76 LEU A 25 LEU A 62 LEU A 22	None	1.13A	1mx1B-2mjmA: 2.2	1mx1B-2mjmA: 10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_A_ZMRA1478_1 (NEURAMINIDASE)	2mjm	PROTEIN NLRC5 (Mus musculus)	4 / 7	SER A 10 ASP A 7 SER A 96 TRP A 98	None	1.13A	2cmlA-2mjmA: undetectable	2cmlA-2mjmA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_B_ZMRB2478_1 (NEURAMINIDASE)	2mjm	PROTEIN NLRC5 (Mus musculus)	4 / 8	SER A 10 ASP A 7 SER A 96 TRP A 98	None	1.14A	2cmlB-2mjmA: undetectable	2cmlB-2mjmA: 13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K8M_A_ACRA720_1 (ALPHA-AMYLASE, SUSG)	2mjm	PROTEIN NLRC5 (Mus musculus)	4 / 7	GLU A 16 TRP A 19 LEU A 62 TRP A 73	None	0.86A	3k8mA-2mjmA: undetectable	3k8mA-2mjmA: 8.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M10_A_NCAA603_0 (CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE)	2mjm	PROTEIN NLRC5 (Mus musculus)	4 / 5	LEU A 84 PHE A 76 LEU A 22 TRP A 32	None	1.14A	5m10A-2mjmA: undetectable	5m10A-2mjmA: 11.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1MX1_B_THAB2_1","LIVER CARBOXYLESTERASE I","2mjm","PROTEIN NLRC5","Mus musculus",5,"LEU A  80;PHE A  76;LEU A  25;LEU A  62;LEU A  22","None","1.13A","1mx1B-2mjmA:2.2","1mx1B-2mjmA:10.15"],["2CML_A_ZMRA1478_1","NEURAMINIDASE","2mjm","PROTEIN NLRC5","Mus musculus",4,"SER A  10;ASP A   7;SER A  96;TRP A  98","None","1.13A","2cmlA-2mjmA:undetectable","2cmlA-2mjmA:13.33"],["2CML_B_ZMRB2478_1","NEURAMINIDASE","2mjm","PROTEIN NLRC5","Mus musculus",4,"SER A  10;ASP A   7;SER A  96;TRP A  98","None","1.14A","2cmlB-2mjmA:undetectable","2cmlB-2mjmA:13.33"],["3K8M_A_ACRA720_1","ALPHA-AMYLASE, SUSG","2mjm","PROTEIN NLRC5","Mus musculus",4,"GLU A  16;TRP A  19;LEU A  62;TRP A  73","None","0.86A","3k8mA-2mjmA:undetectable","3k8mA-2mjmA:8.91"],["5M10_A_NCAA603_0","CYCLOHEXANONE MONOOXYGENASE FROM THERMOCRISPUM MUNICIPALE","2mjm","PROTEIN NLRC5","Mus musculus",4,"LEU A  84;PHE A  76;LEU A  22;TRP A  32","None","1.14A","5m10A-2mjmA:undetectable","5m10A-2mjmA:11.95"]]