SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_A_SPMA201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	2mk6	ADAPTER PROTEIN MECA (Bacillus subtilis)	4 / 6	GLU A 4 GLU A 72 TYR A 14 GLU A 2	None	1.01A	4mi4A-2mk6A: undetectable	4mi4A-2mk6A: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_B_SPMB201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	2mk6	ADAPTER PROTEIN MECA (Bacillus subtilis)	4 / 7	GLU A 4 GLU A 72 TYR A 14 GLU A 2	None	1.01A	4mi4B-2mk6A: undetectable 4mi4C-2mk6A: undetectable	4mi4B-2mk6A: 19.90 4mi4C-2mk6A: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	2mk6	ADAPTER PROTEIN MECA (Bacillus subtilis)	4 / 7	GLU A 4 GLU A 72 TYR A 14 GLU A 2	None	1.02A	4mi4A-2mk6A: undetectable 4mi4C-2mk6A: undetectable	4mi4A-2mk6A: 19.90 4mi4C-2mk6A: 19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_A_SPMA201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	2mk6	ADAPTER PROTEIN MECA (Bacillus subtilis)	4 / 8	GLU A 4 GLU A 72 TYR A 14 GLU A 2	None	1.00A	4mj8A-2mk6A: undetectable 4mj8C-2mk6A: undetectable	4mj8A-2mk6A: 22.03 4mj8C-2mk6A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_B_SPMB201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	2mk6	ADAPTER PROTEIN MECA (Bacillus subtilis)	4 / 8	GLU A 4 GLU A 72 TYR A 14 GLU A 2	None	1.00A	4mj8B-2mk6A: undetectable 4mj8C-2mk6A: undetectable	4mj8B-2mk6A: 22.03 4mj8C-2mk6A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MJ8_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	2mk6	ADAPTER PROTEIN MECA (Bacillus subtilis)	4 / 7	GLU A 4 GLU A 72 TYR A 14 GLU A 2	None	1.02A	4mj8C-2mk6A: undetectable	4mj8C-2mk6A: 22.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4MI4_A_SPMA201_1","SPERMIDINE N1-ACETYLTRANSFERASE","2mk6","ADAPTER PROTEIN MECA","Bacillus subtilis",4,"GLU A   4;GLU A  72;TYR A  14;GLU A   2","None","1.01A","4mi4A-2mk6A:undetectable","4mi4A-2mk6A:19.90"],["4MI4_B_SPMB201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","2mk6","ADAPTER PROTEIN MECA","Bacillus subtilis",4,"GLU A   4;GLU A  72;TYR A  14;GLU A   2","None","1.01A","4mi4B-2mk6A:undetectable;4mi4C-2mk6A:undetectable","4mi4B-2mk6A:19.90;4mi4C-2mk6A:19.90"],["4MI4_C_SPMC201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","2mk6","ADAPTER PROTEIN MECA","Bacillus subtilis",4,"GLU A   4;GLU A  72;TYR A  14;GLU A   2","None","1.02A","4mi4A-2mk6A:undetectable;4mi4C-2mk6A:undetectable","4mi4A-2mk6A:19.90;4mi4C-2mk6A:19.90"],["4MJ8_A_SPMA201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","2mk6","ADAPTER PROTEIN MECA","Bacillus subtilis",4,"GLU A   4;GLU A  72;TYR A  14;GLU A   2","None","1.00A","4mj8A-2mk6A:undetectable;4mj8C-2mk6A:undetectable","4mj8A-2mk6A:22.03;4mj8C-2mk6A:22.03"],["4MJ8_B_SPMB201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","2mk6","ADAPTER PROTEIN MECA","Bacillus subtilis",4,"GLU A   4;GLU A  72;TYR A  14;GLU A   2","None","1.00A","4mj8B-2mk6A:undetectable;4mj8C-2mk6A:undetectable","4mj8B-2mk6A:22.03;4mj8C-2mk6A:22.03"],["4MJ8_C_SPMC201_1","SPERMIDINE N1-ACETYLTRANSFERASE","2mk6","ADAPTER PROTEIN MECA","Bacillus subtilis",4,"GLU A   4;GLU A  72;TYR A  14;GLU A   2","None","1.02A","4mj8C-2mk6A:undetectable","4mj8C-2mk6A:22.03"]]