SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mkk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_B_DVAB8_0
(GRAMICIDIN A)		 2mkk CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 1
(Homo
sapiens) 		3 / 3 VAL A 282
VAL A 264
TRP A 266
 None
 0.91A 1av2A-2mkkA:
undetectable
1av2B-2mkkA:
undetectable		 1av2A-2mkkA:
11.69
1av2B-2mkkA:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 2mkk CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 1
(Homo
sapiens) 		4 / 8 PHE A 256
PHE A 286
LEU A 296
VAL A 328
 None
 0.90A 1fslB-2mkkA:
undetectable		 1fslB-2mkkA:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2mkk CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 361
VAL A 396
ALA A 410
PHE A 412
VAL A 354
 None
 1.34A 2g70A-2mkkA:
undetectable		 2g70A-2mkkA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2mkk CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 361
VAL A 396
ALA A 410
PHE A 412
VAL A 354
 None
 1.35A 2g70B-2mkkA:
undetectable		 2g70B-2mkkA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2mkk CYTOPLASMIC
POLYADENYLATION
ELEMENT-BINDING
PROTEIN 1
(Homo
sapiens) 		5 / 12 LEU A 361
VAL A 396
ALA A 410
PHE A 412
VAL A 354
 None
 1.39A 2g72A-2mkkA:
undetectable		 2g72A-2mkkA:
22.85