SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mks'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUJ_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 2mks RNA-BINDING MOTIF
PROTEIN, X
CHROMOSOME
(Homo
sapiens) 		5 / 8 THR A  21
VAL A  29
VAL A  39
LEU A  41
VAL A  56
 None
 1.03A 2zujA-2mksA:
undetectable		 2zujA-2mksA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2mks RNA-BINDING MOTIF
PROTEIN, X
CHROMOSOME
(Homo
sapiens) 		5 / 12 ILE A  36
THR A  21
LEU A  17
PHE A  13
MET A  42
 None
 1.24A 4zdyA-2mksA:
undetectable		 4zdyA-2mksA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 2mks RNA-BINDING MOTIF
PROTEIN, X
CHROMOSOME
(Homo
sapiens) 		4 / 6 VAL A  56
LEU A  26
MET A  71
LEU A  76
 None
 0.92A 6f6sA-2mksA:
undetectable
6f6sB-2mksA:
undetectable		 6f6sA-2mksA:
23.91
6f6sB-2mksA:
22.11