SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ml1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2ml1 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		6 / 12 GLY A  24
ASP A  62
GLY A  39
GLY A  22
ILE A  19
LEU A  46
 CA  A 203 (-4.5A)
CA  A 205 (-3.3A)
CA  A 205 (-4.2A)
CA  A 201 (-4.3A)
None
None
 1.23A 2nxeA-2ml1A:
undetectable		 2nxeA-2ml1A:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 2ml1 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		4 / 7 GLY A  40
GLY A  21
GLU A  61
ALA A  58
 CA  A 203 ( 4.1A)
CA  A 201 (-4.7A)
None
None
 0.87A 3fpjB-2ml1A:
undetectable		 3fpjB-2ml1A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2ml1 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		4 / 4 GLY A  30
GLU A  17
ASP A  34
ASP A  29
 CA  A 202 (-4.4A)
CA  A 202 (-3.4A)
None
None
 1.35A 3mb5A-2ml1A:
undetectable		 3mb5A-2ml1A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2ml1 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		4 / 6 ASP A  62
GLY A  39
ASP A  26
ASP A  73
 CA  A 205 (-3.3A)
CA  A 205 (-4.2A)
CA  A 201 ( 2.5A)
CA  A 205 (-2.2A)
 1.33A 5hp1A-2ml1A:
undetectable		 5hp1A-2ml1A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0I_B_ACTB303_0
(SWI5-DEPENDENT HO
EXPRESSION PROTEIN 2)		 2ml1 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		4 / 5 VAL A 105
THR A 114
ASN A 135
LEU A 140
 None
 1.27A 5m0iB-2ml1A:
undetectable		 5m0iB-2ml1A:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 2ml1 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		5 / 10 ASP A  73
ASP A  29
THR A  47
GLY A  21
ASP A   8
 CA  A 205 (-2.2A)
None
None
CA  A 201 (-4.7A)
CA  A 201 (-3.4A)
 1.50A 6mb9C-2ml1A:
undetectable		 6mb9C-2ml1A:
19.48