SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ml3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		4 / 7 PHE A 137
SER A 150
PHE A  87
LEU A  55
 None
 1.04A 1qcaA-2ml3A:
undetectable		 1qcaA-2ml3A:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		5 / 12 GLY A  33
GLY A  30
GLY A  31
ALA A  50
ASP A  62
 CA  A 203 (-4.4A)
CA  A 203 (-4.4A)
CA  A 203 (-4.5A)
None
CA  A 204 ( 2.6A)
 1.10A 2dpmA-2ml3A:
undetectable		 2dpmA-2ml3A:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA1_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		3 / 3 GLY A  48
ASP A  71
SER A  72
 CA  A 205 (-4.1A)
CA  A 205 (-3.2A)
None
 0.66A 3brfA-2ml3A:
undetectable		 3brfA-2ml3A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		4 / 8 ALA A 151
SER A 111
LEU A 125
TYR A 128
 None
 1.08A 4ijiF-2ml3A:
undetectable		 4ijiF-2ml3A:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		5 / 11 SER A  13
LEU A  77
GLU A  70
ASP A  53
GLY A  48
 None
None
None
CA  A 203 ( 2.4A)
CA  A 205 (-4.1A)
 1.19A 4zjqA-2ml3A:
undetectable		 4zjqA-2ml3A:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHR_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		4 / 5 GLU A 138
TYR A 124
SER A  75
ASP A  82
 None
None
None
CA  A 205 (-2.2A)
 1.48A 5fhrA-2ml3A:
undetectable		 5fhrA-2ml3A:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_A_BEZA301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		5 / 10 GLY A  24
GLY A  42
LEU A  23
GLU A  59
TYR A  40
 CA  A 202 (-4.4A)
CA  A 204 (-4.4A)
None
None
None
 1.33A 5hwkA-2ml3A:
undetectable		 5hwkA-2ml3A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWK_B_BEZB301_0
(GLUTATHIONE-SPECIFIC
GAMMA-GLUTAMYLCYCLOT
RANSFERASE)		 2ml3 POLY(BETA-D-MANNURON
ATE) C5 EPIMERASE 6
(Azotobacter
vinelandii) 		5 / 10 GLY A  24
GLY A  42
LEU A  23
GLU A  59
TYR A  40
 CA  A 202 (-4.4A)
CA  A 204 (-4.4A)
None
None
None
 1.33A 5hwkB-2ml3A:
undetectable		 5hwkB-2ml3A:
19.76