SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mlb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A9J_A_TYLA1188_1 (BROMODOMAIN CONTAINING 2)	2mlb	REDESIGNED UBIQUITIN (synthetic construct)	4 / 5	VAL A 18 LEU A 27 LEU A 57 ILE A 68	None	0.78A	4a9jA-2mlbA: undetectable	4a9jA-2mlbA: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A9J_B_TYLB1187_1 (BROMODOMAIN CONTAINING 2)	2mlb	REDESIGNED UBIQUITIN (synthetic construct)	4 / 5	VAL A 18 LEU A 27 LEU A 57 ILE A 68	None	0.78A	4a9jB-2mlbA: undetectable	4a9jB-2mlbA: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A9J_C_TYLC1184_1 (BROMODOMAIN CONTAINING 2)	2mlb	REDESIGNED UBIQUITIN (synthetic construct)	4 / 5	VAL A 18 LEU A 27 LEU A 57 ILE A 68	None	0.80A	4a9jC-2mlbA: undetectable	4a9jC-2mlbA: 18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC0_A_RBFA303_2 (RIBOFLAVIN TRANSPORTER RIBU)	2mlb	REDESIGNED UBIQUITIN (synthetic construct)	3 / 3	LYS A 43 LEU A 27 ILE A 68	None	0.71A	5kc0A-2mlbA: undetectable	5kc0A-2mlbA: 18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KC4_A_RBFA201_2 (RIBOFLAVIN TRANSPORTER RIBU)	2mlb	REDESIGNED UBIQUITIN (synthetic construct)	3 / 3	LYS A 43 LEU A 27 ILE A 68	None	0.72A	5kc4A-2mlbA: undetectable	5kc4A-2mlbA: 17.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4A9J_A_TYLA1188_1","BROMODOMAIN CONTAINING 2","2mlb","REDESIGNED UBIQUITIN","synthetic construct",4,"VAL A  18;LEU A  27;LEU A  57;ILE A  68","None","0.78A","4a9jA-2mlbA:undetectable","4a9jA-2mlbA:18.83"],["4A9J_B_TYLB1187_1","BROMODOMAIN CONTAINING 2","2mlb","REDESIGNED UBIQUITIN","synthetic construct",4,"VAL A  18;LEU A  27;LEU A  57;ILE A  68","None","0.78A","4a9jB-2mlbA:undetectable","4a9jB-2mlbA:18.83"],["4A9J_C_TYLC1184_1","BROMODOMAIN CONTAINING 2","2mlb","REDESIGNED UBIQUITIN","synthetic construct",4,"VAL A  18;LEU A  27;LEU A  57;ILE A  68","None","0.80A","4a9jC-2mlbA:undetectable","4a9jC-2mlbA:18.83"],["5KC0_A_RBFA303_2","RIBOFLAVIN TRANSPORTER RIBU","2mlb","REDESIGNED UBIQUITIN","synthetic construct",3,"LYS A  43;LEU A  27;ILE A  68","None","0.71A","5kc0A-2mlbA:undetectable","5kc0A-2mlbA:18.29"],["5KC4_A_RBFA201_2","RIBOFLAVIN TRANSPORTER RIBU","2mlb","REDESIGNED UBIQUITIN","synthetic construct",3,"LYS A  43;LEU A  27;ILE A  68","None","0.72A","5kc4A-2mlbA:undetectable","5kc4A-2mlbA:17.82"]]