SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mlk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2mlk RSTA
(Klebsiella
pneumoniae) 		3 / 3 SER A 162
ALA A 160
VAL A 159
 None
 0.49A 4o2bA-2mlkA:
undetectable		 4o2bA-2mlkA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2mlk RSTA
(Klebsiella
pneumoniae) 		3 / 3 SER A 162
ALA A 160
VAL A 159
 None
 0.54A 4o2bC-2mlkA:
undetectable		 4o2bC-2mlkA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 2mlk RSTA
(Klebsiella
pneumoniae) 		4 / 6 ARG A 182
LYS A 223
ARG A 209
ILE A 205
 None
 1.43A 5a06A-2mlkA:
undetectable		 5a06A-2mlkA:
21.76