SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mmy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_A_FFOA1293_1 (SERINE HYDROXYMETHYLTRANSFE RASE)	2mmy	TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N (Homo sapiens)	3 / 3	GLU A 285 TYR A 274 PHE A 237	None	0.56A	1eqbB-2mmyA: undetectable	1eqbB-2mmyA: 13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_B_FFOB2293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2mmy	TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N (Homo sapiens)	3 / 3	GLU A 285 TYR A 274 PHE A 237	None	0.57A	1eqbA-2mmyA: undetectable	1eqbA-2mmyA: 13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_C_FFOC3293_2 (SERINE HYDROXYMETHYLTRANSFE RASE)	2mmy	TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N (Homo sapiens)	3 / 3	GLU A 285 TYR A 274 PHE A 237	None	0.57A	1eqbD-2mmyA: undetectable	1eqbD-2mmyA: 13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQB_D_FFOD4293_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2mmy	TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N (Homo sapiens)	3 / 3	GLU A 285 TYR A 274 PHE A 237	None	0.57A	1eqbC-2mmyA: undetectable	1eqbC-2mmyA: 13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	2mmy	TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N (Homo sapiens)	5 / 12	PHE A 253 PHE A 290 ILE A 236 VAL A 315 PHE A 303	None	1.28A	6ap6A-2mmyA: undetectable	6ap6A-2mmyA: 15.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1EQB_A_FFOA1293_1","SERINE HYDROXYMETHYLTRANSFERASE","2mmy","TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N","Homo sapiens",3,"GLU A 285;TYR A 274;PHE A 237","None","0.56A","1eqbB-2mmyA:undetectable","1eqbB-2mmyA:13.49"],["1EQB_B_FFOB2293_0","SERINE HYDROXYMETHYLTRANSFERASE","2mmy","TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N","Homo sapiens",3,"GLU A 285;TYR A 274;PHE A 237","None","0.57A","1eqbA-2mmyA:undetectable","1eqbA-2mmyA:13.49"],["1EQB_C_FFOC3293_2","SERINE HYDROXYMETHYLTRANSFERASE","2mmy","TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N","Homo sapiens",3,"GLU A 285;TYR A 274;PHE A 237","None","0.57A","1eqbD-2mmyA:undetectable","1eqbD-2mmyA:13.49"],["1EQB_D_FFOD4293_0","SERINE HYDROXYMETHYLTRANSFERASE","2mmy","TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N","Homo sapiens",3,"GLU A 285;TYR A 274;PHE A 237","None","0.57A","1eqbC-2mmyA:undetectable","1eqbC-2mmyA:13.49"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","2mmy","TATA-BINDING PROTEIN-ASSOCIATED FACTOR 2N","Homo sapiens",5,"PHE A 253;PHE A 290;ILE A 236;VAL A 315;PHE A 303","None","1.28A","6ap6A-2mmyA:undetectable","6ap6A-2mmyA:15.79"]]