SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mna'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OTV_A_NCAA1301_0 (CATIONIC TRYPSIN)	2mna	SINGLE-STRANDED DNA BINDING PROTEIN (SSB) (Sulfolobus solfataricus)	4 / 6	ASP A 46 VAL A 51 GLY A 6 GLY A 49	None	0.78A	2otvA-2mnaA: undetectable	2otvA-2mnaA: 17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_C_CHDC150_0 (ILEAL BILE ACID-BINDING PROTEIN)	2mna	SINGLE-STRANDED DNA BINDING PROTEIN (SSB) (Sulfolobus solfataricus)	5 / 12	GLN A 82 VAL A 44 LEU A 53 ILE A 43 THR A 54	None	1.38A	3elzC-2mnaA: undetectable	3elzC-2mnaA: 22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UR0_C_SVRC516_1 (RNA-DEPENDENT RNA POLYMERASE)	2mna	SINGLE-STRANDED DNA BINDING PROTEIN (SSB) (Sulfolobus solfataricus)	5 / 9	GLY A 88 ALA A 87 TRP A 56 ALA A 60 LEU A 53	None	1.17A	3ur0C-2mnaA: undetectable	3ur0C-2mnaA: 12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAS_B_ADNB401_2 (PUTATIVE ADENOSINE KINASE)	2mna	SINGLE-STRANDED DNA BINDING PROTEIN (SSB) (Sulfolobus solfataricus)	4 / 5	LEU A 8 ALA A 114 MET A 12 THR A 76	None	1.35A	3vasB-2mnaA: undetectable	3vasB-2mnaA: 20.92

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2OTV_A_NCAA1301_0","CATIONIC TRYPSIN","2mna","SINGLE-STRANDED DNA BINDING PROTEIN (SSB)","Sulfolobus solfataricus",4,"ASP A  46;VAL A  51;GLY A   6;GLY A  49","None","0.78A","2otvA-2mnaA:undetectable","2otvA-2mnaA:17.70"],["3ELZ_C_CHDC150_0","ILEAL BILE ACID-BINDING PROTEIN","2mna","SINGLE-STRANDED DNA BINDING PROTEIN (SSB)","Sulfolobus solfataricus",5,"GLN A  82;VAL A  44;LEU A  53;ILE A  43;THR A  54","None","1.38A","3elzC-2mnaA:undetectable","3elzC-2mnaA:22.07"],["3UR0_C_SVRC516_1","RNA-DEPENDENT RNA POLYMERASE","2mna","SINGLE-STRANDED DNA BINDING PROTEIN (SSB)","Sulfolobus solfataricus",5,"GLY A  88;ALA A  87;TRP A  56;ALA A  60;LEU A  53","None","1.17A","3ur0C-2mnaA:undetectable","3ur0C-2mnaA:12.23"],["3VAS_B_ADNB401_2","PUTATIVE ADENOSINE KINASE","2mna","SINGLE-STRANDED DNA BINDING PROTEIN (SSB)","Sulfolobus solfataricus",4,"LEU A   8;ALA A 114;MET A  12;THR A  76","None","1.35A","3vasB-2mnaA:undetectable","3vasB-2mnaA:20.92"]]