SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2moq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		4 / 8 ILE A 223
LEU A 211
LEU A 129
LEU A 125
 None
 0.79A 4zvcA-2moqA:
undetectable
4zvcB-2moqA:
undetectable		 4zvcA-2moqA:
18.75
4zvcB-2moqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVC_A_BEZA301_0
(DIGUANYLATE CYCLASE
DOSC)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		4 / 8 LEU A 129
LEU A 125
ILE A 223
LEU A 211
 None
 0.77A 4zvcA-2moqA:
undetectable
4zvcB-2moqA:
undetectable		 4zvcA-2moqA:
18.75
4zvcB-2moqA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		5 / 12 VAL A 200
PHE A 198
ILE A 209
ILE A 223
ILE A 185
 None
 0.94A 5uvmB-2moqA:
undetectable		 5uvmB-2moqA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		3 / 3 LEU A 207
THR A 179
ASN A 262
 None
 0.70A 6baaE-2moqA:
undetectable		 6baaE-2moqA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		3 / 3 LEU A 207
THR A 179
ASN A 262
 None
 0.70A 6baaF-2moqA:
undetectable		 6baaF-2moqA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		3 / 3 LEU A 207
THR A 179
ASN A 262
 None
 0.71A 6baaG-2moqA:
undetectable		 6baaG-2moqA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_2
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		3 / 3 LEU A 207
THR A 179
ASN A 262
 None
 0.71A 6baaH-2moqA:
undetectable		 6baaH-2moqA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		3 / 3 PHE A 194
ARG A 130
GLN A 193
 None
 1.17A 6g1pB-2moqA:
undetectable		 6g1pB-2moqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2moq IRON-REGULATED
SURFACE DETERMINANT
PROTEIN B
(Staphylococcus
aureus) 		3 / 3 PHE A 242
ARG A 130
GLN A 193
 None
 0.99A 6g1pB-2moqA:
undetectable		 6g1pB-2moqA:
20.41