SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mou'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_B_BZMB600_0
(ODORANT-BINDING
PROTEIN)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		5 / 9 ILE A 144
VAL A 171
ASN A 148
GLY A 177
LEU A 179
 None
 1.27A 1dzmB-2mouA:
0.0		 1dzmB-2mouA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		5 / 10 GLY A  16
VAL A  14
MET A 124
ILE A 126
TYR A 120
 None
 1.43A 1pn0B-2mouA:
undetectable		 1pn0B-2mouA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		3 / 3 ARG A 109
ASP A  75
ASP A  70
 None
 0.84A 2ejtA-2mouA:
undetectable		 2ejtA-2mouA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		5 / 12 ASN A 191
ILE A  97
ASP A 110
GLY A 146
ASN A 148
 None
 1.37A 4djfA-2mouA:
undetectable		 4djfA-2mouA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		3 / 3 SER A 100
ALA A 102
VAL A 103
 None
 0.55A 4o2bA-2mouA:
undetectable		 4o2bA-2mouA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		3 / 3 SER A 100
ALA A 102
VAL A 103
 None
 0.65A 4o2bC-2mouA:
undetectable		 4o2bC-2mouA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_C_FOLC201_0
(FOLATE ECF
TRANSPORTER)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		5 / 12 ARG A 176
SER A 131
THR A 187
LEU A  78
ARG A  71
 None
 1.49A 4z7fC-2mouA:
undetectable		 4z7fC-2mouA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_A_AG2A501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		4 / 6 SER A 100
GLY A 146
ASN A 148
ILE A  97
 None
 1.00A 5j4nA-2mouA:
undetectable		 5j4nA-2mouA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2mou STAR-RELATED LIPID
TRANSFER PROTEIN 6
(Homo
sapiens) 		3 / 3 THR A  10
SER A 128
ASP A  90
 None
 0.84A 5kvaA-2mouA:
undetectable		 5kvaA-2mouA:
24.04