SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mp4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 2mp4 ACTIN-DEPOLYMERIZING
FACTOR 1, ISOFORMS
A/B
(Caenorhabditis
elegans) 		5 / 12 VAL A  84
PHE A  30
VAL A  11
LEU A 133
THR A 135
 None
 0.83A 1oq5A-2mp4A:
undetectable		 1oq5A-2mp4A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 2mp4 ACTIN-DEPOLYMERIZING
FACTOR 1, ISOFORMS
A/B
(Caenorhabditis
elegans) 		5 / 12 VAL A  84
PHE A  30
VAL A  11
LEU A 133
THR A 135
 None
 0.88A 1z9yA-2mp4A:
undetectable		 1z9yA-2mp4A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 2mp4 ACTIN-DEPOLYMERIZING
FACTOR 1, ISOFORMS
A/B
(Caenorhabditis
elegans) 		4 / 8 ASP A  56
TYR A  25
ASP A  53
GLU A  24
 None
 0.97A 4xjeA-2mp4A:
undetectable		 4xjeA-2mp4A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2mp4 ACTIN-DEPOLYMERIZING
FACTOR 1, ISOFORMS
A/B
(Caenorhabditis
elegans) 		3 / 3 LEU A 158
ILE A 105
TYR A  27
 None
 0.69A 5uunB-2mp4A:
undetectable		 5uunB-2mp4A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 2mp4 ACTIN-DEPOLYMERIZING
FACTOR 1, ISOFORMS
A/B
(Caenorhabditis
elegans) 		5 / 12 VAL A  84
PHE A  30
VAL A  11
LEU A 133
THR A 135
 None
 0.86A 6bccA-2mp4A:
undetectable		 6bccA-2mp4A:
18.93