SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mpa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RMT_B_ADNB1502_1 (CLASS B ACID PHOSPHATASE)	2mpa	MN12H2 IGG2A-KAPPA,HEAVY CHAIN (Mus musculus)	4 / 7	PHE H 154 LEU H 178 THR H 125 TYR H 153	None	1.24A	1rmtB-2mpaH: undetectable	1rmtB-2mpaH: 21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BXQ_A_IMNA2001_1 (SERUM ALBUMIN)	2mpa	MN12H2 IGG2A-KAPPA,HEAVY CHAIN (Mus musculus)	5 / 10	SER H 75 PHE H 29 ALA H 24 LEU H 4 LEU H 34	None	1.04A	2bxqA-2mpaH: undetectable	2bxqA-2mpaH: 16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OF4_B_ACTB313_0 (NITROREDUCTASE)	2mpa	MN12H2 IGG2A-KAPPA,HEAVY CHAIN (Mus musculus)	3 / 3	ALA H 176 VAL H 177 GLN H 179	None	0.65A	3of4B-2mpaH: undetectable	3of4B-2mpaH: 23.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5MTH_A_ACTA302_0 (ANTIBODY FAB HEAVY CHAIN)	2mpa	MN12H2 IGG2A-KAPPA,HEAVY CHAIN (Mus musculus)	4 / 5	SER H 120 ALA H 122 PHE H 154 LEU H 178	None	0.37A	5mthA-2mpaH: 26.5	5mthA-2mpaH: 73.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIW_D_LOCD503_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA CHAIN)	2mpa	MN12H2 IGG2A-KAPPA,HEAVY CHAIN (Mus musculus)	3 / 3	SER H 211 ALA H 206 VAL H 205	None	0.50A	5xiwC-2mpaH: undetectable	5xiwC-2mpaH: 18.30

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RMT_B_ADNB1502_1","CLASS B ACID PHOSPHATASE","2mpa","MN12H2 IGG2A-KAPPA,HEAVY CHAIN","Mus musculus",4,"PHE H 154;LEU H 178;THR H 125;TYR H 153","None","1.24A","1rmtB-2mpaH:undetectable","1rmtB-2mpaH:21.31"],["2BXQ_A_IMNA2001_1","SERUM ALBUMIN","2mpa","MN12H2 IGG2A-KAPPA,HEAVY CHAIN","Mus musculus",5,"SER H  75;PHE H  29;ALA H  24;LEU H   4;LEU H  34","None","1.04A","2bxqA-2mpaH:undetectable","2bxqA-2mpaH:16.52"],["3OF4_B_ACTB313_0","NITROREDUCTASE","2mpa","MN12H2 IGG2A-KAPPA,HEAVY CHAIN","Mus musculus",3,"ALA H 176;VAL H 177;GLN H 179","None","0.65A","3of4B-2mpaH:undetectable","3of4B-2mpaH:23.65"],["5MTH_A_ACTA302_0","ANTIBODY FAB HEAVY CHAIN","2mpa","MN12H2 IGG2A-KAPPA,HEAVY CHAIN","Mus musculus",4,"SER H 120;ALA H 122;PHE H 154;LEU H 178","None","0.37A","5mthA-2mpaH:26.5","5mthA-2mpaH:73.42"],["5XIW_D_LOCD503_1","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA CHAIN","2mpa","MN12H2 IGG2A-KAPPA,HEAVY CHAIN","Mus musculus",3,"SER H 211;ALA H 206;VAL H 205","None","0.50A","5xiwC-2mpaH:undetectable","5xiwC-2mpaH:18.30"]]