SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mpe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A15_A_NCAA1001_0 (HYPOTHETICAL PROTEIN RV0760C)	2mpe	BPSL1050 (Burkholderia pseudomallei)	5 / 11	ILE A 51 LEU A 68 LEU A 126 LEU A 123 TYR A 92	None	1.28A	2a15A-2mpeA: undetectable	2a15A-2mpeA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RIW_A_T44A1395_1 (THYROXINE-BINDING GLOBULIN)	2mpe	BPSL1050 (Burkholderia pseudomallei)	5 / 10	ALA A 33 LEU A 123 LEU A 70 LEU A 68 ARG A 107	None	1.19A	2riwA-2mpeA: undetectable 2riwB-2mpeA: undetectable	2riwA-2mpeA: 17.46 2riwB-2mpeA: 13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_B_SVRB512_1 (PHOSPHOLIPASE A2)	2mpe	BPSL1050 (Burkholderia pseudomallei)	5 / 5	VAL A 37 VAL A 38 THR A 15 THR A 35 ARG A 50	None	1.46A	3bjwA-2mpeA: undetectable	3bjwA-2mpeA: 20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB201_0 (HYDROXYNITRILE LYASE)	2mpe	BPSL1050 (Burkholderia pseudomallei)	5 / 11	VAL A 109 PHE A 111 ILE A 25 ILE A 51 LEU A 123	None	1.07A	5e4dB-2mpeA: undetectable	5e4dB-2mpeA: 18.10

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2A15_A_NCAA1001_0","HYPOTHETICAL PROTEIN RV0760C","2mpe","BPSL1050","Burkholderia pseudomallei",5,"ILE A  51;LEU A  68;LEU A 126;LEU A 123;TYR A  92","None","1.28A","2a15A-2mpeA:undetectable","2a15A-2mpeA:18.57"],["2RIW_A_T44A1395_1","THYROXINE-BINDING GLOBULIN;THYROXINE-BINDING GLOBULIN","2mpe","BPSL1050","Burkholderia pseudomallei",5,"ALA A  33;LEU A 123;LEU A  70;LEU A  68;ARG A 107","None","1.19A","2riwA-2mpeA:undetectable;2riwB-2mpeA:undetectable","2riwA-2mpeA:17.46;2riwB-2mpeA:13.60"],["3BJW_B_SVRB512_1","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","2mpe","BPSL1050","Burkholderia pseudomallei",5,"VAL A  37;VAL A  38;THR A  15;THR A  35;ARG A  50","None","1.46A","3bjwA-2mpeA:undetectable","3bjwA-2mpeA:20.29"],["5E4D_B_BEZB201_0","HYDROXYNITRILE LYASE","2mpe","BPSL1050","Burkholderia pseudomallei",5,"VAL A 109;PHE A 111;ILE A  25;ILE A  51;LEU A 123","None","1.07A","5e4dB-2mpeA:undetectable","5e4dB-2mpeA:18.10"]]