SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mpo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 2mpo MIC2-ASSOCIATED
PROTEIN
(Toxoplasma
gondii) 		3 / 3 VAL A 158
VAL A  36
ASP A 126
 None
 0.66A 2fumD-2mpoA:
undetectable		 2fumD-2mpoA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKK_A_SAMA301_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 2mpo MIC2-ASSOCIATED
PROTEIN
(Toxoplasma
gondii) 		5 / 12 GLY A  75
ILE A  66
ASN A  34
LEU A  97
GLU A  94
 None
 1.15A 3ckkA-2mpoA:
undetectable		 3ckkA-2mpoA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V8V_B_SAMB801_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE L)		 2mpo MIC2-ASSOCIATED
PROTEIN
(Toxoplasma
gondii) 		5 / 11 GLY A  48
SER A  52
ASP A  50
ASN A 173
LEU A 178
 None
 1.21A 3v8vB-2mpoA:
undetectable		 3v8vB-2mpoA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA813_0
(GEPHYRIN)		 2mpo MIC2-ASSOCIATED
PROTEIN
(Toxoplasma
gondii) 		3 / 3 THR A 170
ALA A 165
LYS A  26
 None
 0.73A 6fgcA-2mpoA:
undetectable		 6fgcA-2mpoA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA817_0
(GEPHYRIN)		 2mpo MIC2-ASSOCIATED
PROTEIN
(Toxoplasma
gondii) 		3 / 3 THR A 170
ALA A 165
LYS A  26
 None
 0.76A 6fgdA-2mpoA:
undetectable		 6fgdA-2mpoA:
19.04