SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mpr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.25A 1rs6A-2mprA:
undetectable		 1rs6A-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.13A 1rs6B-2mprA:
undetectable		 1rs6B-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 7 LEU A  44
THR A  40
ALA A  42
VAL A  68
 None
 0.94A 1tyrB-2mprA:
undetectable		 1tyrB-2mprA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.25A 1zzqA-2mprA:
undetectable		 1zzqA-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.11A 1zzqB-2mprA:
undetectable		 1zzqB-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_B_TRPB603_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		5 / 12 GLY A  18
GLY A  15
THR A  14
GLU A 416
GLN A  21
 None
 1.27A 2azxB-2mprA:
undetectable		 2azxB-2mprA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR2_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		5 / 11 GLY A  18
GLY A  15
THR A  14
GLU A 416
GLN A  21
 None
 1.29A 2dr2A-2mprA:
undetectable		 2dr2A-2mprA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		5 / 7 GLY A 277
THR A 236
TYR A 234
ASP A 308
ASN A 276
 None
 1.43A 2g70A-2mprA:
undetectable		 2g70A-2mprA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		5 / 7 GLY A 277
THR A 236
TYR A 234
ASP A 308
ASN A 276
 None
 1.40A 2g70B-2mprA:
undetectable		 2g70B-2mprA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 6 GLY A 277
TYR A 234
ASP A 308
ASN A 276
 None
 1.13A 2g72A-2mprA:
undetectable		 2g72A-2mprA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 7 ARG A   8
GLU A  43
TYR A 118
ARG A 109
 GLC  A 429 (-3.0A)
GLC  A 429 ( 2.6A)
BGC  A 428 (-4.4A)
GLC  A 429 ( 3.0A)
 1.21A 2zt7A-2mprA:
undetectable		 2zt7A-2mprA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.30A 3n62B-2mprA:
undetectable		 3n62B-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.28A 3n66B-2mprA:
undetectable		 3n66B-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 THR A 147
ARG A 248
GLY A 151
SER A 253
 None
 0.96A 3tzfB-2mprA:
undetectable		 3tzfB-2mprA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		3 / 3 THR A 216
VAL A 231
GLU A 188
 None
 0.77A 3v4tA-2mprA:
undetectable
3v4tD-2mprA:
undetectable		 3v4tA-2mprA:
23.79
3v4tD-2mprA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 5 TRP A 417
GLY A 420
ALA A 377
PHE A  23
 None
 1.39A 3wqwA-2mprA:
undetectable		 3wqwA-2mprA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_A_IMNA201_1
(TRANSTHYRETIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 7 LEU A  44
THR A  40
ALA A  42
VAL A  68
 None
 1.01A 4ik7A-2mprA:
undetectable		 4ik7A-2mprA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 2mpr MALTOPORIN
(Salmonella
enterica) 		3 / 3 ASP A 173
TYR A 107
TRP A 120
 None
 1.35A 4p7nA-2mprA:
undetectable		 4p7nA-2mprA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.29A 5vunA-2mprA:
undetectable		 5vunA-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.23A 5vunB-2mprA:
undetectable		 5vunB-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.22A 5vuoB-2mprA:
undetectable		 5vuoB-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 6 PRO A  96
GLY A  97
ASN A  90
LYS A  89
 None
 0.95A 5xxiA-2mprA:
undetectable		 5xxiA-2mprA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		3 / 3 GLN A  29
TRP A 315
VAL A 341
 None
 0.79A 6auuA-2mprA:
undetectable		 6auuA-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2mpr MALTOPORIN
(Salmonella
enterica) 		4 / 8 ARG A 109
GLN A  87
ASN A  63
ASP A  61
 GLC  A 429 ( 3.0A)
None
None
None
 1.22A 6auuB-2mprA:
undetectable		 6auuB-2mprA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2mpr MALTOPORIN
(Salmonella
enterica) 		3 / 3 GLY A 151
THR A 167
GLU A 148
 None
 0.61A 6b58A-2mprA:
undetectable		 6b58A-2mprA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2mpr MALTOPORIN
(Salmonella
enterica) 		5 / 10 VAL A 318
VAL A 336
TYR A 353
TYR A 338
GLY A 319
 None
 1.15A 6bsjA-2mprA:
undetectable		 6bsjA-2mprA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2mpr MALTOPORIN
(Salmonella
enterica) 		3 / 3 PHE A  23
ARG A 411
GLN A  21
 None
 0.91A 6g1pB-2mprA:
undetectable		 6g1pB-2mprA:
21.33