SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mpv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QHF_A_ACTA507_0 (CHORISMATE SYNTHASE)	2mpv	MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA (Escherichia coli)	3 / 3	LEU A 37 ASN A 24 ARG A 25	None	0.83A	2qhfA-2mpvA: undetectable	2qhfA-2mpvA: 17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NBQ_B_URFB400_1 (URIDINE PHOSPHORYLASE 1)	2mpv	MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA (Escherichia coli)	4 / 8	GLY A 58 GLN A 64 LEU A 130 ILE A 41	None	0.71A	3nbqB-2mpvA: undetectable	3nbqB-2mpvA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NBQ_C_URFC400_1 (URIDINE PHOSPHORYLASE 1)	2mpv	MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA (Escherichia coli)	4 / 8	GLY A 58 GLN A 64 LEU A 130 ILE A 41	None	0.70A	3nbqC-2mpvA: undetectable	3nbqC-2mpvA: 18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BW4_B_SAMB301_0 (16S RRNA (ADENINE(1408)-N(1)) -METHYLTRANSFERASE)	2mpv	MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA (Escherichia coli)	5 / 12	GLY A 58 ALA A 132 ILE A 41 LEU A 66 LEU A 130	None	1.05A	5bw4B-2mpvA: undetectable	5bw4B-2mpvA: 18.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QHF_A_ACTA507_0","CHORISMATE SYNTHASE","2mpv","MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA","Escherichia coli",3,"LEU A  37;ASN A  24;ARG A  25","None","0.83A","2qhfA-2mpvA:undetectable","2qhfA-2mpvA:17.70"],["3NBQ_B_URFB400_1","URIDINE PHOSPHORYLASE 1","2mpv","MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA","Escherichia coli",4,"GLY A  58;GLN A  64;LEU A 130;ILE A  41","None","0.71A","3nbqB-2mpvA:undetectable","3nbqB-2mpvA:18.58"],["3NBQ_C_URFC400_1","URIDINE PHOSPHORYLASE 1","2mpv","MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA","Escherichia coli",4,"GLY A  58;GLN A  64;LEU A 130;ILE A  41","None","0.70A","3nbqC-2mpvA:undetectable","3nbqC-2mpvA:18.58"],["5BW4_B_SAMB301_0","16S RRNA (ADENINE(1408)-N(1))-METHYLTRANSFERASE","2mpv","MAJOR FIMBRIAL SUBUNIT OF AGGREGATIVE ADHERENCE FIMBRIA II AAFA","Escherichia coli",5,"GLY A  58;ALA A 132;ILE A  41;LEU A  66;LEU A 130","None","1.05A","5bw4B-2mpvA:undetectable","5bw4B-2mpvA:18.73"]]