SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mq9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 2mq9 EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1
(Homo
sapiens) 		5 / 12 GLY A  98
GLY A  29
VAL A  95
VAL A 110
TYR A 125
 None
 1.31A 1n2xA-2mq9A:
undetectable		 1n2xA-2mq9A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 2mq9 EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1
(Homo
sapiens) 		4 / 7 ILE A  14
ILE A  17
LYS A  18
THR A 133
 None
 0.92A 1sbrB-2mq9A:
undetectable		 1sbrB-2mq9A:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 2mq9 EUKARYOTIC PEPTIDE
CHAIN RELEASE FACTOR
SUBUNIT 1
(Homo
sapiens) 		3 / 3 LYS A 109
SER A  33
SER A  70
 None
 0.82A 6gbfA-2mq9A:
undetectable		 6gbfA-2mq9A:
16.22