SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2mqb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_1
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2mqb PROBABLE
BETA-LACTAMASE
(Staphylococcus
aureus) 		4 / 4 THR A  95
LEU A  98
VAL A  14
LEU A  10
 None
 0.95A 1fbmB-2mqbA:
undetectable		 1fbmB-2mqbA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4G_B_RIOB501_0
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 2mqb PROBABLE
BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 9 ASP A  80
GLY A  26
SER A  21
ASP A  89
THR A  93
 None
 1.46A 1m4gB-2mqbA:
0.0		 1m4gB-2mqbA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 2mqb PROBABLE
BETA-LACTAMASE
(Staphylococcus
aureus) 		4 / 7 SER A  17
ILE A 146
ILE A  23
THR A  93
 None
 0.89A 1sbrB-2mqbA:
undetectable		 1sbrB-2mqbA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 2mqb PROBABLE
BETA-LACTAMASE
(Staphylococcus
aureus) 		4 / 8 GLY A  26
THR A  83
ILE A  24
ASN A  22
 None
 0.94A 2a8tB-2mqbA:
undetectable		 2a8tB-2mqbA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_B_RIMB299_1
(MATRIX PROTEIN 2)		 2mqb PROBABLE
BETA-LACTAMASE
(Staphylococcus
aureus) 		4 / 6 LEU A  94
LEU A  98
TRP A  91
ILE A 112
 None
 1.02A 2rlfB-2mqbA:
undetectable
2rlfC-2mqbA:
undetectable		 2rlfB-2mqbA:
10.46
2rlfC-2mqbA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2mqb PROBABLE
BETA-LACTAMASE
(Staphylococcus
aureus) 		5 / 9 GLY A  50
GLY A  26
VAL A  76
ASN A  29
ILE A  19
 None
 1.15A 3owxA-2mqbA:
undetectable		 3owxA-2mqbA:
21.24