SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2ms7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN
(Homo
sapiens) 		3 / 3 ALA A  74
VAL A  69
TRP A  68
 None
 0.83A 1kqeA-2ms7A:
undetectable
1kqeE-2ms7A:
undetectable		 1kqeA-2ms7A:
12.12
1kqeE-2ms7A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN
(Homo
sapiens) 		3 / 3 ALA A  74
VAL A  69
TRP A  68
 None
 0.82A 1kqeB-2ms7A:
undetectable
1kqeD-2ms7A:
undetectable		 1kqeB-2ms7A:
12.12
1kqeD-2ms7A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN
(Homo
sapiens) 		3 / 3 TRP A  68
ALA A  74
VAL A  69
 None
 0.83A 1kqeB-2ms7A:
undetectable
1kqeD-2ms7A:
undetectable		 1kqeB-2ms7A:
12.12
1kqeD-2ms7A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN
(Homo
sapiens) 		3 / 3 TRP A  68
ALA A  74
VAL A  69
 None
 0.83A 1kqeA-2ms7A:
undetectable
1kqeE-2ms7A:
undetectable		 1kqeA-2ms7A:
12.12
1kqeE-2ms7A:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MIC_A_DVAA6_0
(GRAMICIDIN A)		 2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN
(Homo
sapiens) 		3 / 3 ALA A  74
VAL A  69
TRP A  68
 None
 0.91A 1micA-2ms7A:
undetectable
1micB-2ms7A:
undetectable		 1micA-2ms7A:
11.27
1micB-2ms7A:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN
(Homo
sapiens) 		3 / 3 PHE A  59
TRP A  68
GLU A   5
 None
 1.08A 1mogA-2ms7A:
undetectable		 1mogA-2ms7A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2ms7 MITOCHONDRIAL
ANTIVIRAL-SIGNALING
PROTEIN
(Homo
sapiens) 		4 / 8 ALA A  85
ILE A  73
CYH A  79
GLY A  78
 None
 0.73A 1sv9A-2ms7A:
undetectable		 1sv9A-2ms7A:
20.34